Medical office space · data as of September 2026
Medical office space for lease in Encino
15 buildings with 114,607 SF of medical space available across 66 listed spaces. Eight buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
The newest of the 15 buildings with medical space listed in Encino went up in 1988.
Year built isn't a verdict on any one suite. But in a building from the 1970s, whether a suite can take exam rooms comes down to plumbing, ADA restrooms and HVAC capacity, and that decides the build-out budget before the rent does. The 15 buildings run from 1923 to 1988, median 1970.
The second thing to know is about location. Encino Hospital Medical Center is 0.7 mile from the center of the trade area. From the real estate side, a short distance to a campus is worth paying for only if it's the drive your practice actually makes. Pay for that, and negotiate everything else.
Put together: the newest building went up in 1988, and Encino Hospital Medical Center sits 0.7 mile out. The address is fixed the day you sign; almost everything else is negotiable. How often does your practice make the trip to Encino Hospital Medical Center now?
Encino at a glance
- Buildings
- 15
- Medical space available
- 114,607 SF
- Vacant now
- 94,652 SF
- Largest single space
- 6,049 SF
Asking rents by lease structure
- Full Service$2.50–$3.75/SF/mo3 buildings
- Modified Gross$1.99–$3.50/SF/mo3 buildings
- Lease type not stated$2.65–$3.75/SF/mo2 buildings
7 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms26
- 3–4 rooms23
- 5–7 rooms7
- 8–12 rooms6
- 13+ rooms0
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class A5
- Class B8
- Class C2
Hospitals within 5 miles
- Encino Hospital Medical Center, Encino0.7 mi
- Providence Cedars Sinai Tarzana Medical Center, Tarzana2.0 mi
- Sherman Oaks Hospital, Sherman Oaks2.8 mi
- Valley Presbyterian Hospital, Van Nuys3.0 mi
- Northridge Hospital Medical Center, Northridge4.5 mi
Straight-line miles from the center of the Encino buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 6345 Balboa Blvd Encino Crossing I | A | 1988 | 24,044 SF10 spaces
| 4,794 SF | ~7–12 rooms | $3.25/SF/mo Full Service | |
| 16633 Ventura Blvd Encino Executive Tower | A | 1970 | 16,681 SF4 spaces
| 5,715 SF | ~9–14 rooms | Withheld ask us | |
| 5400 Balboa Blvd Encino Medical Plaza | B | 1973 | 10,197 SF4 spaces
| 6,049 SF | ~10–15 rooms | Withheld ask us | |
| 16250 Ventura Blvd Encino Office Bldg | C | 1972 | 10,150 SF4 spaces
| 4,919 SF | ~8–12 rooms | $1.99–$3.45/SF/mo Modified Gross | |
| 15840 Ventura Blvd | B | 1966 | 9,890 SF9 spaces
| 1,901 SF | ~3–4 rooms | Withheld ask us | |
| 16661 Ventura Blvd | B | 1966 | 9,793 SF9 spaces
| 1,694 SF | ~2–4 rooms | Withheld ask us | |
| 16200 Ventura Blvd | C | 1964 | 6,436 SF9 spaces
| 2,204 SF | ~3–5 rooms | $2.65–$3.07/SF/mo | |
| 16260 Ventura Blvd Encino Medical Tower | A | 1964 | 4,731 SF5 spaces
| 1,200 SF | ~2–3 rooms | $3.75/SF/mo | |
| 17323 Ventura Blvd | B | 1987 | 4,380 SF1 space
| 4,380 SF | ~7–11 rooms | $2.75/SF/mo Modified Gross | |
| 16542 Ventura Blvd Rubio Plaza East | A | 1960 | 3,888 SF2 spaces
| 3,208 SF | ~5–8 rooms | $3.75/SF/mo Full Service | |
| 16952 Ventura Blvd | B | 1923 | 3,695 SF1 space
| 3,695 SF | ~6–9 rooms | Withheld ask us | |
| 17525 Ventura Blvd | B | 1980 | 3,439 SF2 spaces
| 2,116 SF | ~3–5 rooms | Withheld ask us | |
| 5353-5363 Balboa Blvd West Valley Medical Center | B | 1952 | 2,768 SF2 spaces
| 1,567 SF | ~2–4 rooms | $3.50/SF/mo Modified Gross | |
| 16133 Ventura Blvd Encino Financial Center | A | 1975 | 2,276 SF2 spaces
| 1,241 SF | ~2–3 rooms | $2.50–$3.30/SF/mo Full Service | |
| 17609 Ventura Blvd | B | 1980 | 2,239 SF2 spaces
| 1,206 SF | ~2–3 rooms | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Encino | 15 | 114,607 SF | Full Service $2.50–$3.75 (3) · Modified Gross $1.99–$3.50 (3) · Lease type not stated $2.65–$3.75 (2) |
| Tarzana | 28 | 157,473 SF | Modified Gross $2.00–$4.48 (10) · Full Service $1.85–$6.00 (7) · NNN $2.50–$4.20 (5) |
| Sherman Oaks | 11 | 53,923 SF | Full Service $2.00–$3.75 (5) · Modified Gross $2.45 (1) |
| Western San Fernando Valley | 44 | 237,184 SF | Full Service $1.80–$3.75 (12) · Modified Gross $1.75–$4.40 (11) · NNN $2.00–$3.35 (6) |
| Los Angeles overall | 849 | 6,324,965 SF | Modified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Encino
How many medical office buildings have space available in Encino?
Encino has 15 buildings with medical office space available as of September 2026: 114,607 SF across 66 listed spaces. Of that, 94,652 SF is marked vacant now, and the largest single space is 6,049 SF, about 10 to 15 exam rooms.
What do medical office leases cost in Encino?
In Encino, six buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class A on Full Service in three, Class B on Modified Gross in two and Class C on Modified Gross in one. Another seven buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Encino?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Encino, the listed spaces break down as 26 for 1 to 2 rooms, 23 for 3 to 4, 7 for 5 to 7 and 6 for 8 to 12.
Which hospitals are near Encino?
Encino Hospital Medical Center is the closest hospital, 0.7 mile from the center of the Encino trade area. Also within 5 miles: Providence Cedars Sinai Tarzana Medical Center, Tarzana, 2.0 miles; Sherman Oaks Hospital, Sherman Oaks, 2.8 miles; Valley Presbyterian Hospital, Van Nuys, 3.0 miles; Northridge Hospital Medical Center, Northridge, 4.5 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Encino availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Encino
Send your size and timing. Live availability comes back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.
Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
- Lighthouse Pediatrics4,261 SFTorrance
- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine