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Medical office space · data as of September 2026

Medical office space for lease in Tarzana

28 buildings with 157,473 SF of medical space available across 67 listed spaces. The largest like group, seven Class B buildings on Full Service, asks a median $3.15/SF/month.

The center of the Tarzana buildings is 0.6 mile from Providence Cedars Sinai Tarzana Medical Center.

That's straight-line distance from the middle of 28 buildings, so individual buildings sit closer or farther. Across the trade area, the largest like group, seven Class B buildings on Full Service, asks a median $3.15/SF/month, and five post no asking rent. Most of the inventory sits on Ventura Blvd and Burbank Blvd: 16 of 28 buildings.

One more fact changes the read. Landlords here quote three lease structures: Modified Gross in 10 buildings, at $2.00 to $4.48/SF/month; Full Service in seven buildings and NNN in five buildings. The lease read: convert every quote to total occupancy cost before comparing a single number. An NNN rate can look cheaper than a Full Service rate and cost more. Every lease structure should be approached differently during Operating Expense reconciliations.

Put together: Providence Cedars Sinai Tarzana Medical Center sits 0.6 mile out, and landlords there quote three lease structures. Comparing rates without converting structures compares labels. Is your current lease Full Service, NNN or Modified Gross, and do you know what it costs all in?

Tarzana at a glance

Buildings
28
Medical space available
157,473 SF
Vacant now
142,715 SF
Largest single space
10,000 SF

Asking rents by lease structure

  • Modified Gross$2.00–$4.48/SF/mo10 buildings
  • Full Service$1.85–$6.00/SF/mo7 buildings
  • NNN$2.50–$4.20/SF/mo5 buildings
  • Lease type not stated$2.50–$3.50/SF/mo1 building

5 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.

Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.

Available spaces by size

  • 1–2 rooms18
  • 3–4 rooms25
  • 5–7 rooms18
  • 8–12 rooms4
  • 13+ rooms2

Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.

Building class

  • Class A1
  • Class B23
  • Class C4

Hospitals within 5 miles

  • Providence Cedars Sinai Tarzana Medical Center, Tarzana0.6 mi
  • Kaiser Foundation Hospital - Woodland Hills, Woodland Hills2.6 mi
  • Encino Hospital Medical Center, Encino3.3 mi
  • Northridge Hospital Medical Center, Northridge3.4 mi
  • Valley Presbyterian Hospital, Van Nuys4.8 mi

Straight-line miles from the center of the Tarzana buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.

Buildings with medical space available

BuildingClassBuiltMedical spaceLargest spaceFitsAsking rent
5525 Etiwanda Ave
Tarzana Medical Plaza
B198627,633 SF
8 spaces
  • Suite 114 · 10,000 SF · available now
  • Suite 110/112 · 2,696 to 6,145 SF · available now
  • Suite 220 · 1,682 SF · available now
  • Suite 217 · 1,218 SF · available now
  • Suite 324 · 3,947 SF · available now
  • Suite 315 · 1,621 SF · available now
  • Suite 309 · 1,577 SF · available now
  • Suite 305 · 1,443 SF · available now
10,000 SF~16–25 roomsWithheld
ask us
18321 Ventura Blvd
Tarzana Tower
B197421,664 SF
8 spaces
  • Suite 210 · 1,744 SF · available now
  • Suite 230 · 1,562 SF · available now
  • Suite 255 · 1,212 SF · available now
  • Suite 215 · 1,142 SF · available now
  • Suite 330 · 2,553 SF · available now
  • Suite 420 · 3,806 SF · available now
  • Suite 515 · 1,084 SF · available now
  • Suite 1000 · 1,019 to 8,561 SF · available now
8,561 SF~14–22 rooms$1.99/SF/mo
Full Service
17835 Ventura Blvd
Encino Towers
B197214,784 SF
9 spaces
  • Suite Suite · 625 SF · available now
  • Floor 1 · 528 SF · available now
  • Suite 209 · 3,210 SF · available now
  • Suite 210 · 3,114 SF · available now
  • Suite 204 · 3,034 SF · available now
  • Suite 207 · 910 SF · available now
  • Suite 208 · 879 SF · available now
  • Suite 203 · 723 SF · available now
  • Suite 301 · 1,761 SF · available now
3,210 SF~5–8 roomsWithheld
ask us
5620 Wilbur Ave
Wilbur Medical Plaza
B19869,349 SF
5 spaces
  • Suite 210 · 2,171 SF · available now
  • Suite 214 · 1,306 SF · available now
  • Suite 320 · 3,207 SF · available now
  • Suite 309 · 1,448 SF · available now
  • Suite 307 · 1,217 SF · available now
3,207 SF~5–8 roomsWithheld
ask us
18801 Ventura Blvd
Tarzana Financial Center
B19829,125 SF
2 spaces
  • Suite 200 · 1,800 to 3,877 SF · available now
  • Suite 300 · 5,248 SF · available now
5,248 SF~8–13 rooms$1.85/SF/mo
Full Service
18425 Burbank Blvd
Tarzana Exchange
B19827,933 SF
2 spaces
  • Floor 1 · 3,973 SF · sublease · available now
  • Suite 413 · 918 to 3,960 SF · available now
3,973 SF~6–10 rooms$2.00/SF/mo
Modified Gross
5647 Beckford AveB20206,585 SF
1 space
  • Floor 1 · 6,585 SF · available now
6,585 SF~10–17 rooms$2.43/SF/mo
Modified Gross
18740 Ventura Blvd
Tarzana Medical Center
B19626,541 SF
5 spaces
  • Suite 106 · 963 SF · available now
  • Suite 205 · 2,452 SF · available now
  • Suite 209 · 1,133 SF · available now
  • Suite 307 · 1,323 SF · available now
  • Suite 303 · 670 SF · available now
2,452 SF~4–6 rooms$3.15/SF/mo
Full Service
19730 Ventura Blvd
Corbin Village Offices Bldg C
B19554,500 SF
1 space
  • Floor 1 · 4,500 SF · available in 30 days
4,500 SF~7–11 rooms$2.75/SF/mo
NNN
18370 Burbank BlvdB19764,357 SF
2 spaces
  • Suite 310 · 502 SF · available now
  • Suite 614 · 3,855 SF · available now
3,855 SF~6–10 roomsWithheld
ask us
19567 Oxnard StC19864,261 SF
2 spaces
  • Floor 1 (full floor) · 2,131 SF · available now
  • Floor 2 (full floor) · 2,130 SF · available now
2,131 SF~3–5 rooms$2.22/SF/mo
Modified Gross
19100 Ventura Blvd
Antigua Square
B19884,245 SF
2 spaces
  • Suite 16 · 3,143 SF · available now
  • Suite 5,6,9,20 · 443 to 1,102 SF · available now
3,143 SF~5–8 rooms$3.25–$3.50/SF/mo
NNN
19500-19510 Ventura BlvdA19823,861 SF
2 spaces
  • Suite 210 · 2,000 SF · available now
  • Suite 214 · 1,861 SF · available now
2,000 SF~3–5 rooms$4.20/SF/mo
NNN
19100 Victory BlvdB19533,780 SF
1 space
  • Floor 1 (full floor) · 3,780 SF · available now
3,780 SF~6–9 rooms$3.71/SF/mo
Modified Gross
18411 Clark St
Tarzana Garden Plaza
B19853,592 SF
2 spaces
  • Suite 204 · 2,021 SF · available now
  • Suite 306 · 1,571 SF · available in 30 days
2,021 SF~3–5 rooms$3.95/SF/mo
Full Service
18226 Ventura Blvd
Thrifty Oil Bldg
B19913,581 SF
1 space
  • Suite 102 · 3,581 SF · available Dec 2026
3,581 SF~5–9 rooms$3.15–$6.00/SF/mo
Full Service
18345 Ventura BlvdB19653,337 SF
2 spaces
  • Suite 104 · 2,062 SF · available now
  • Suite 202 · 1,275 SF · available now
2,062 SF~3–5 rooms$2.65/SF/mo
Full Service
18555 Ventura BlvdC19492,651 SF
1 space
  • Suite C · 2,651 SF · available Feb 2027
2,651 SF~4–6 rooms$4.25/SF/mo
Modified Gross
5932 Lubao AveB19502,455 SF
1 space
  • Floor 1 (full floor) · 2,455 SF · available in 120 days
2,455 SF~4–6 rooms$4.48/SF/mo
Modified Gross
20040-20060 Ventura Blvd
Taft Plaza
B19602,400 SF
1 space
  • Suite 20046 · 2,400 SF · available now
2,400 SF~4–6 rooms$4.17/SF/mo
NNN
18032 Ventura BlvdC19551,980 SF
2 spaces
  • Floor 1 · 150 to 1,000 SF · available now
  • Floor 1 · 200 to 980 SF · available now
1,000 SF~1–2 rooms$2.50–$3.50/SF/mo
5554 Reseda BlvdB19701,800 SF
1 space
  • Suite 101 · 1,800 SF · available now
1,800 SF~3–4 rooms$3.50/SF/mo
Modified Gross
18840-18850 Ventura Blvd
Rimal Medical Building
B19741,625 SF
1 space
  • Suite 212 · 1,625 SF · available now
1,625 SF~2–4 rooms$3.90/SF/mo
Full Service
18401 Burbank Blvd
Tarzana Exchange
B19771,500 SF
1 space
  • Suite 120 · 581 to 1,500 SF · available now
1,500 SF~2–3 rooms$2.00/SF/mo
Modified Gross
18607 Ventura Blvd
Tarzana Town Plaza
B19851,000 SF
1 space
  • Suite 240 · 1,000 SF · sublease · available now
1,000 SF~1–2 roomsWithheld
ask us
17725 Rhoda StC19511,000 SF
1 space
  • Suite A · 1,000 SF · available now
1,000 SF~1–2 rooms$3.50/SF/mo
Modified Gross
20011 Ventura BlvdB2016987 SF
1 space
  • Floor 1 · 987 SF · available now
987 SF~1–2 rooms$2.50/SF/mo
NNN
18455 Burbank Blvd
Tarzana Offices & Medical Buildings
B1963947 SF
1 space
  • Suite 210 · 947 SF · available now
947 SF~1–2 rooms$2.00/SF/mo
Modified Gross

Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.

Compared to nearby

AreaBuildingsMedical spacePublished asking rents ($/SF/mo, buildings)
Tarzana28157,473 SFModified Gross $2.00–$4.48 (10) · Full Service $1.85–$6.00 (7) · NNN $2.50–$4.20 (5)
Encino15114,607 SFFull Service $2.50–$3.75 (3) · Modified Gross $1.99–$3.50 (3) · Lease type not stated $2.65–$3.75 (2)
Western San Fernando Valley44237,184 SFFull Service $1.80–$3.75 (12) · Modified Gross $1.75–$4.40 (11) · NNN $2.00–$3.35 (6)
Woodland Hills and Warner Center15223,624 SFFull Service $2.00–$3.40 (5) · Modified Gross $1.70–$3.00 (3) · NNN $4.00 (1)
Los Angeles overall8496,324,965 SFModified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143)

Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.

Questions about medical office space in Tarzana

How many medical office buildings have space available in Tarzana?

Tarzana has 28 buildings with medical office space available as of September 2026: 157,473 SF across 67 listed spaces. Of that, 142,715 SF is marked vacant now, and the largest single space is 10,000 SF, about 16 to 25 exam rooms.

What do medical office leases cost in Tarzana?

In Tarzana, Class B buildings on Full Service ask $1.85 to $4.58/SF/month, with a median of $3.15, across seven buildings built from 1962 to 1991. Class B on Modified Gross: $2.00 to $4.48, median $2.43, across seven buildings built from 1950 to 2020. Each building counts once, at the middle of its published range. Across the San Fernando Valley, Class B buildings on Full Service ask a median $2.74/SF/month. The remaining nine priced buildings sit in classes and structures with fewer than five buildings each, too few to call typical. Another five buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.

How much space does a medical practice need in Tarzana?

About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Tarzana, the listed spaces break down as 18 for 1 to 2 rooms, 25 for 3 to 4, 18 for 5 to 7, 4 for 8 to 12 and 2 for 13 or more.

Which hospitals are near Tarzana?

Providence Cedars Sinai Tarzana Medical Center is the closest hospital, 0.6 mile from the center of the Tarzana trade area. Also within 5 miles: Kaiser Foundation Hospital - Woodland Hills, Woodland Hills, 2.6 miles; Encino Hospital Medical Center, Encino, 3.3 miles; Northridge Hospital Medical Center, Northridge, 3.4 miles; Valley Presbyterian Hospital, Van Nuys, 4.8 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.

How current is the Tarzana availability?

It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.

Send me what fits in Tarzana

Send your size and timing. Live availability comes back within one business day.

Sent.

We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Jamal Brown, Real Estate Broker

Your advisor

Jamal Brown

Real Estate Broker · CA DRE #01780052

Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.

(619) 796-3390

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