Medical office space · data as of September 2026
Medical office space for lease in Sherman Oaks
11 buildings with 53,923 SF of medical space available across 24 listed spaces. Six buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Sherman Oaks Hospital sits 0.3 mile from the center of the Sherman Oaks trade area.
Those are straight-line miles, measured from the middle of the 11 buildings with space listed, which hold 53,923 SF across 24 spaces. Most of the inventory sits on Van Nuys Blvd and Riverside Dr: 7 of 11 buildings. Across the trade area, six buildings publish an asking rent, and five post no asking rent.
One more fact changes the read. The newest of the 11 buildings went up in 1990, and eight of them are Class B. The lease read: tour with the build-out in mind, not the lobby. Ask what the plumbing, restrooms and HVAC can carry before you talk rent, and get the answer priced into the tenant improvement allowance (the landlord's contribution to build-out).
So: Sherman Oaks Hospital sits 0.3 mile out, and the newest building went up in 1990. The build-out decides this deal as much as the rent does. How many exam rooms, sinks and restrooms does your next suite need?
Sherman Oaks at a glance
- Buildings
- 11
- Medical space available
- 53,923 SF
- Vacant now
- 38,523 SF
- Largest single space
- 8,260 SF
Asking rents by lease structure
- Full Service$2.00–$3.75/SF/mo5 buildings
- Modified Gross$2.45/SF/mo1 building
5 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms6
- 3–4 rooms12
- 5–7 rooms3
- 8–12 rooms2
- 13+ rooms1
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B8
- Class C3
Hospitals within 5 miles
- Sherman Oaks Hospital, Sherman Oaks0.3 mi
- Encino Hospital Medical Center, Encino2.3 mi
- Valley Presbyterian Hospital, Van Nuys2.7 mi
- Kaiser Foundation Hospital - Panorama City, Panorama City4.5 mi
- Mission Community Hospital, Panorama City4.5 mi
Straight-line miles from the center of the Sherman Oaks buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 4849 Van Nuys Blvd Sherman Oaks Medical Center | C | 1965 | 14,494 SF3 spaces
| 8,260 SF | ~13–21 rooms | $3.25/SF/mo Full Service | |
| 4955 Van Nuys Blvd | C | 1968 | 12,132 SF7 spaces
| 3,787 SF | ~6–9 rooms | Withheld ask us | |
| 4312 Woodman Ave | B | 1990 | 8,000 SF2 spaces
| 4,000 SF | ~6–10 rooms | $2.45/SF/mo Modified Gross | |
| 5170 Sepulveda Blvd Sherman Oaks Centrium | B | 1984 | 5,024 SF1 space
| 5,024 SF | ~8–13 rooms | $2.00/SF/mo Full Service | |
| 4419 Van Nuys Blvd | B | 1962 | 4,987 SF3 spaces
| 2,056 SF | ~3–5 rooms | $2.18–$3.25/SF/mo Full Service | |
| 14622 Ventura Blvd La Reina Plaza | C | 1938 | 3,569 SF2 spaces
| 1,788 SF | ~2–4 rooms | Withheld ask us | |
| 4835 Van Nuys Blvd Sherman Oaks Medical Center | B | 1954 | 2,143 SF2 spaces
| 1,344 SF | ~2–3 rooms | Withheld ask us | |
| 4405 Saugus Ave | B | 1947 | 1,277 SF1 space
| 1,277 SF | ~2–3 rooms | Withheld ask us | |
| 13320 Riverside Dr Riverside Medical Bldg | B | 1956 | 942 SF1 space
| 942 SF | ~1–2 rooms | $3.50/SF/mo Full Service | |
| 4910 Van Nuys Blvd Sherman Oaks Medical Arts Center | B | 1985 | 785 SF1 space
| 785 SF | ~1–2 rooms | $3.75/SF/mo Full Service | |
| 13701 Riverside Dr US Bank Bldg | B | 1966 | 570 SF1 space
| 570 SF | ~1 room | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Sherman Oaks | 11 | 53,923 SF | Full Service $2.00–$3.75 (5) · Modified Gross $2.45 (1) |
| Encino | 15 | 114,607 SF | Full Service $2.50–$3.75 (3) · Modified Gross $1.99–$3.50 (3) · Lease type not stated $2.65–$3.75 (2) |
| Studio City and Universal City | 7 | 34,749 SF | Full Service $2.75–$3.65 (3) · Modified Gross $3.75–$4.00 (3) · Lease type not stated $3.50–$3.60 (1) |
| North Hollywood | 6 | 9,106 SF | Modified Gross $2.00–$3.75 (3) · Full Service $2.25 (1) |
| Los Angeles overall | 849 | 6,324,965 SF | Modified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Sherman Oaks
How many medical office buildings have space available in Sherman Oaks?
Sherman Oaks has 11 buildings with medical office space available as of September 2026: 53,923 SF across 24 listed spaces. Of that, 38,523 SF is marked vacant now, and the largest single space is 8,260 SF, about 13 to 21 exam rooms.
What do medical office leases cost in Sherman Oaks?
In Sherman Oaks, six buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Full Service in four, Class C on Full Service in one and Class B on Modified Gross in one. Across the San Fernando Valley, Class B buildings on Full Service ask a median $2.74/SF/month. Another five buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Sherman Oaks?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Sherman Oaks, the listed spaces break down as 6 for 1 to 2 rooms, 12 for 3 to 4, 3 for 5 to 7, 2 for 8 to 12 and 1 for 13 or more.
Which hospitals are near Sherman Oaks?
Sherman Oaks Hospital is the closest hospital, 0.3 mile from the center of the Sherman Oaks trade area. Also within 5 miles: Encino Hospital Medical Center, Encino, 2.3 miles; Valley Presbyterian Hospital, Van Nuys, 2.7 miles; Kaiser Foundation Hospital - Panorama City, Panorama City, 4.5 miles; Mission Community Hospital, Panorama City, 4.5 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Sherman Oaks availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Sherman Oaks
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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