Medical office space · data as of September 2026
Medical office space for lease in Eastern San Fernando Valley
28 buildings with 159,048 SF of medical space available across 72 listed spaces. 16 buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Of the 72 spaces listed in Eastern San Fernando Valley this September, only five are 4,200 SF or larger.
At 385 to 600 rentable SF per exam room (the room plus its share of waiting, work areas and halls), 4,200 SF holds about 7 to 10 rooms. Most of what's listed here is smaller: nine spaces suit one or two rooms and 53 fit three to seven. The largest single space is 11,305 SF, about 18 to 29 rooms.
The second thing to know is about location. Mission Community Hospital is 0.9 mile from the center of the trade area, and Kaiser Foundation Hospital - Panorama City is 1.2 miles. From the real estate side, a short distance to a campus is worth paying for only if it's the drive your practice actually makes. Pay for that, and negotiate everything else.
Short version: only 5 of 72 spaces are 4,200 SF or larger, and two hospitals sit within 1.2 miles of the center. The address is fixed the day you sign; almost everything else is negotiable. How far is your current office from the campus you use most?
Eastern San Fernando Valley at a glance
- Buildings
- 28
- Medical space available
- 159,048 SF
- Vacant now
- 130,896 SF
- Largest single space
- 11,305 SF
Asking rents by lease structure
- Modified Gross$2.00–$3.45/SF/mo6 buildings
- Full Service$2.00–$4.00/SF/mo4 buildings
- NNN$1.70–$4.00/SF/mo3 buildings
- Net$2.00/SF/mo1 building
- Lease type not stated$2.35–$2.99/SF/mo2 buildings
12 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms9
- 3–4 rooms41
- 5–7 rooms12
- 8–12 rooms2
- 13+ rooms3
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B15
- Class C13
Hospitals within 5 miles
- Mission Community Hospital, Panorama City0.9 mi
- Kaiser Foundation Hospital - Panorama City, Panorama City1.2 mi
- Valley Presbyterian Hospital, Van Nuys2.7 mi
- Pacifica Hospital of the Valley, Sun Valley3.0 mi
- Providence Holy Cross Medical Center, Mission Hills3.5 mi
Straight-line miles from the center of the Eastern San Fernando Valley buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 15243 Vanowen St J & D Gerlach Bldg | B | 1971 | 38,119 SF20 spaces
| 3,262 SF | ~5–8 rooms | Withheld ask us | |
| 11550 Indian Hills Rd Holy Cross Medical Plaza | B | 1986 | 16,005 SF6 spaces
| 10,620 SF | ~17–27 rooms | Withheld ask us | |
| 15535 San Fernando Mission Blvd | B | 1991 | 14,445 SF2 spaces
| 11,305 SF | ~18–29 rooms | $3.00/SF/mo Full Service | |
| 11600 Indian Hills Rd GREATER VALLEY MEDICAL GROUP | B | 1997 | 12,196 SF2 spaces
| 6,641 SF | ~11–17 rooms | Withheld ask us | |
| 6840-6850 Sepulveda Blvd | B | 1969 | 9,011 SF6 spaces
| 2,789 SF | ~4–7 rooms | Withheld ask us | |
| 14624 Sherman Way Valley Medical Plaza II | C | 1981 | 8,554 SF5 spaces
| 2,226 SF | ~3–5 rooms | Withheld ask us | |
| 14600 Sherman Way Valley Medical Plaza I | C | 1990 | 7,508 SF1 space
| 7,508 SF | ~12–19 rooms | Withheld ask us | |
| 8025-8065 Webb Ave Lankershim Plaza | B | 1996 | 6,682 SF3 spaces
| 3,432 SF | ~5–8 rooms | Withheld ask us | |
| 14416-14420 Chase St | C | 1953 | 5,080 SF2 spaces
| 2,961 SF | ~4–7 rooms | $2.35/SF/mo | |
| 412-418 San Fernando Mission Blvd | C | 1957 | 3,750 SF1 space
| 3,750 SF | ~6–9 rooms | $2.25/SF/mo Modified Gross | |
| 15211 Vanowen St | B | 1981 | 3,658 SF2 spaces
| 2,324 SF | ~3–6 rooms | Withheld ask us | |
| 14901 Rinaldi St Holy Cross Hospital Campus | B | 1993 | 3,500 SF2 spaces
| 2,300 SF | ~3–5 rooms | $4.00/SF/mo Full Service | |
| 7138 Van Nuys Blvd | C | 1957 | 3,351 SF1 space
| 3,351 SF | ~5–8 rooms | Withheld ask us | |
| 6815 Noble Ave Southern California Orthopedic Institute | B | 1991 | 3,200 SF1 space
| 3,200 SF | ~5–8 rooms | Withheld ask us | |
| 6742 Van Nuys Blvd | C | 1970 | 2,910 SF5 spaces
| 1,500 SF | ~2–3 rooms | $2.25–$3.40/SF/mo Modified Gross | |
| 7838-7840 Vantage Ave | B | 1948 | 2,575 SF1 space
| 2,575 SF | ~4–6 rooms | Withheld ask us | |
| 14622 Victory Blvd | C | 1963 | 2,200 SF1 space
| 2,200 SF | ~3–5 rooms | $2.99/SF/mo | |
| 14533 Vanowen St | C | 1949 | 2,000 SF1 space
| 2,000 SF | ~3–5 rooms | $2.00/SF/mo Net | |
| 11024 Sepulveda Blvd | C | 1955 | 2,000 SF1 space
| 2,000 SF | ~3–5 rooms | Withheld ask us | |
| 15333-15339 Sherman Way Sherman Way Center | B | 1985 | 1,850 SF1 space
| 1,850 SF | ~3–4 rooms | $2.75/SF/mo Modified Gross | |
| 326-328 N Maclay Ave | C | 1960 | 1,800 SF1 space
| 1,800 SF | ~3–4 rooms | $4.00/SF/mo NNN | |
| 9722 Laurel Canyon Blvd | C | 1981 | 1,750 SF1 space
| 1,750 SF | ~2–4 rooms | $3.45/SF/mo Modified Gross | |
| 14124 Foothill Blvd | B | 2003 | 1,586 SF1 space
| 1,586 SF | ~2–4 rooms | $2.35/SF/mo NNN | |
| 15216 Vanowen St | B | 1959 | 1,260 SF1 space
| 1,260 SF | ~2–3 rooms | $1.70/SF/mo NNN | |
| 8809 Sunland Blvd | B | 1957 | 1,249 SF1 space
| 1,249 SF | ~2–3 rooms | $2.50/SF/mo Modified Gross | |
| 403-405 N MacLay Ave Court Plaza | C | 1980 | 1,234 SF1 space
| 1,234 SF | ~2–3 rooms | $3.81/SF/mo Full Service | |
| 8215 Van Nuys Blvd Panorama Medical Arts Bldg | C | 1957 | 1,075 SF1 space
| 1,075 SF | ~1–2 rooms | $2.00/SF/mo Full Service | |
| 6850 Van Nuys Blvd 6850 Van Nuys Boulevard | B | 1956 | 500 SF1 space
| 500 SF | ~1 room | $2.00–$2.40/SF/mo Modified Gross |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Eastern San Fernando Valley | 28 | 159,048 SF | Modified Gross $2.00–$3.45 (6) · Full Service $2.00–$4.00 (4) · NNN $1.70–$4.00 (3) |
| North Hollywood | 6 | 9,106 SF | Modified Gross $2.00–$3.75 (3) · Full Service $2.25 (1) |
| Sherman Oaks | 11 | 53,923 SF | Full Service $2.00–$3.75 (5) · Modified Gross $2.45 (1) |
| Western San Fernando Valley | 44 | 237,184 SF | Full Service $1.80–$3.75 (12) · Modified Gross $1.75–$4.40 (11) · NNN $2.00–$3.35 (6) |
| Los Angeles overall | 849 | 6,324,965 SF | Modified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Eastern San Fernando Valley
How many medical office buildings have space available in Eastern San Fernando Valley?
Eastern San Fernando Valley has 28 buildings with medical office space available as of September 2026: 159,048 SF across 72 listed spaces. Of that, 130,896 SF is marked vacant now, and the largest single space is 11,305 SF, about 18 to 29 exam rooms.
What do medical office leases cost in Eastern San Fernando Valley?
In Eastern San Fernando Valley, 14 buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Modified Gross in three, Class C on Modified Gross in three and Class B on Full Service in two. Another 12 buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Eastern San Fernando Valley?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Eastern San Fernando Valley, the listed spaces break down as 9 for 1 to 2 rooms, 41 for 3 to 4, 12 for 5 to 7, 2 for 8 to 12 and 3 for 13 or more.
Which hospitals are near Eastern San Fernando Valley?
Mission Community Hospital is the closest hospital, 0.9 mile from the center of the Eastern San Fernando Valley trade area. Also within 5 miles: Kaiser Foundation Hospital - Panorama City, Panorama City, 1.2 miles; Valley Presbyterian Hospital, Van Nuys, 2.7 miles; Pacifica Hospital of the Valley, Sun Valley, 3.0 miles; Providence Holy Cross Medical Center, Mission Hills, 3.5 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Eastern San Fernando Valley availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Eastern San Fernando Valley
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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