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Medical office space · data as of September 2026

Medical office space for lease in Escondido

11 buildings with 130,076 SF of medical space available across 22 listed spaces. Six buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.

Palomar Health Downtown Campus sits 0.7 mile from the center of the Escondido trade area.

That's straight-line distance from the middle of 11 buildings, so individual buildings sit closer or farther. Across the trade area, six buildings publish an asking rent, and four post no asking rent. Of the 11 buildings, 3 sit on Citracado Pky.

The second thing to know is about price. Landlords here quote three lease structures: NNN in three buildings, at $1.65 to $2.50/SF/month; Modified Gross in two buildings and Full Service in one building. The lease read: convert every quote to total occupancy cost before comparing a single number. An NNN rate can look cheaper than a Full Service rate and cost more.

Put together: Palomar Health Downtown Campus sits 0.7 mile out, and landlords there quote three lease structures. Convert every quote to the same basis before any number looks cheap. When you set a quote here next to your current rent, are you comparing the same structure?

Escondido at a glance

Buildings
11
Medical space available
130,076 SF
Vacant now
53,004 SF
Largest single space
25,000 SF

Asking rents by lease structure

  • NNN$1.60–$2.50/SF/mo3 buildings
  • Modified Gross$1.75–$2.95/SF/mo2 buildings
  • Full Service$2.58/SF/mo1 building

4 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.

Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.

Available spaces by size

  • 1–2 rooms2
  • 3–4 rooms10
  • 5–7 rooms2
  • 8–12 rooms4
  • 13+ rooms4

Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.

Building class

  • Class A1
  • Class B6
  • Class C4

Hospitals within 5 miles

  • Palomar Health Downtown Campus, Escondido0.7 mi
  • Kaiser Foundation Hospital - San Marcos, San Marcos4.7 mi

Straight-line miles from the center of the Escondido buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.

Buildings with medical space available

BuildingClassBuiltMedical spaceLargest spaceFitsAsking rent
2127 W Citracado Pky
Palomar Health Phase III
B202275,000 SF
3 spaces
  • Floor 1 (full floor) · 1,500 to 25,000 SF · sublease · available in 30 days
  • Floor 2 (full floor) · 1,500 to 25,000 SF · sublease · available in 30 days
  • Floor 3 (full floor) · 1,500 to 25,000 SF · sublease · available in 30 days
25,000 SF~41–64 roomsWithheld
ask us
625 W Citracado Pky
Citracado Medical Plaza
B200716,441 SF
5 spaces
  • Suite 120 · 1,269 SF · available in 30 days
  • Suite 110 · 803 SF · available in 30 days
  • Suite 200 · 6,901 SF · available now
  • Suite 203 · 5,375 SF · available now
  • Suite 206 · 2,093 SF · available now
6,901 SF~11–17 roomsWithheld
ask us
1955 Citracado Pky
Madison Medical Center
A201112,717 SF
3 spaces
  • Suite 200 · 7,698 SF · sublease · available now
  • Suite 201 · 1,348 SF · sublease · available now
  • Suite 302 · 3,671 SF · sublease · available now
7,698 SF~12–19 rooms$3.33–$3.45/SF/mo
NNN · sublease
625-643 E Grand AveB196912,411 SF
3 spaces
  • Suite 625 · 6,459 SF · available now
  • Suite 631 · 4,512 SF · available now
  • Suite 643 · 1,440 SF · available now
6,459 SF~10–16 rooms$1.75/SF/mo
Modified Gross
235 W 5th Ave
5th Avenue Corporate Center
B19813,194 SF
1 space
  • Suite 200 · 3,194 SF · available now
3,194 SF~5–8 roomsWithheld
ask us
136-140 W 3rd AveC18962,789 SF
2 spaces
  • Floor 1 · 1,395 SF · available now
  • Floor 2 · 1,394 SF · available now
1,395 SF~2–3 roomsWithheld
ask us
940 E Valley Pky
Vintage Plaza
C19892,210 SF
1 space
  • Suite N · 2,210 SF · available now
2,210 SF~3–5 rooms$2.50/SF/mo
NNN
910 E Grand AveC19801,713 SF
1 space
  • Suite D · 1,713 SF · available now
1,713 SF~2–4 rooms$2.58/SF/mo
Full Service
700 W El Norte Pky
Premiere Building
B19911,600 SF
1 space
  • Suite #101B · 1,600 SF · available now
1,600 SF~2–4 rooms$2.10/SF/mo
NNN
362 W Mission AveC19811,200 SF
1 space
  • Suite 206 · 1,200 SF · available now
1,200 SF~2–3 rooms$1.60–$1.70/SF/mo
NNN
255 N Elm St
Hidden Valley Medical Bldg
B1983801 SF
1 space
  • Suite 205 · 801 SF · available now
801 SF~1–2 rooms$2.95/SF/mo
Modified Gross

Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.

Compared to nearby

AreaBuildingsMedical spacePublished asking rents ($/SF/mo, buildings)
Escondido11130,076 SFNNN $1.60–$2.50 (3) · Modified Gross $1.75–$2.95 (2) · Full Service $2.58 (1)
San Marcos1061,193 SFGross + Electric $2.15–$2.95 (2) · Gross + Utilities $2.20 (2) · Lease type not stated $1.99–$2.05 (1)
Rancho Bernardo981,859 SFNNN $1.60–$3.25 (3) · Modified Gross $2.00–$3.50 (2) · Gross + Electric $2.95–$3.25 (1)
Poway751,906 SFModified Gross $3.25–$4.00 (2)
San Diego overall2462,136,242 SFNNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13)

Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.

Questions about medical office space in Escondido

How many medical office buildings have space available in Escondido?

Escondido has 11 buildings with medical office space available as of September 2026: 130,076 SF across 22 listed spaces. Of that, 53,004 SF is marked vacant now, and the largest single space is 25,000 SF, about 41 to 64 exam rooms.

What do medical office leases cost in Escondido?

In Escondido, six buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Modified Gross in two, Class C on NNN in two and Class C on Full Service in one. Another four buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.

How much space does a medical practice need in Escondido?

About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Escondido, the listed spaces break down as 2 for 1 to 2 rooms, 10 for 3 to 4, 2 for 5 to 7, 4 for 8 to 12 and 4 for 13 or more.

Which hospitals are near Escondido?

Palomar Health Downtown Campus is the closest hospital, 0.7 mile from the center of the Escondido trade area. Also within 5 miles: Kaiser Foundation Hospital - San Marcos, San Marcos, 4.7 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.

How current is the Escondido availability?

It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.

Send me what fits in Escondido

Send your size and timing. Live availability comes back within one business day.

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We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Jamal Brown, Real Estate Broker

Your advisor

Jamal Brown

Real Estate Broker · CA DRE #01780052

Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.

(619) 796-3390

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