Medical office space · data as of September 2026
Medical office space for lease in College Area
15 buildings with 75,453 SF of medical space available across 33 listed spaces. 11 buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Landlords in College Area quote three different lease structures this September: Modified Gross in five buildings, NNN in five and Gross + Utilities & Janitorial in one.
Modified Gross runs $2.35/SF/month here, NNN $1.88 to $3.50 and Gross + Utilities & Janitorial $1.75. Those ranges sit side by side on the page, but they don't measure the same thing. Modified Gross splits operating costs between landlord and tenant, lease by lease; NNN puts taxes, insurance and common-area costs on top of the rate; a Gross + Utilities & Janitorial rate leaves part of the operating cost to the tenant. The only fair comparison is total occupancy cost: the rent plus everything the lease puts on top of it.
One more fact changes the read. Half of the buildings here went up in 1975 or earlier. From the real estate side, an older building can be the better deal, if the landlord pays to make the suite work. Ask what the plumbing, restrooms and HVAC can carry before you talk rent. The rent and the build-out are one negotiation, not two.
So: landlords in College Area quote three lease structures, and the median building dates to 1975. In an older building, the allowance matters as much as the rate. How many exam rooms, sinks and restrooms does your next suite need?
College Area at a glance
- Buildings
- 15
- Medical space available
- 75,453 SF
- Vacant now
- 55,090 SF
- Largest single space
- 9,303 SF
Asking rents by lease structure
- Modified Gross$2.35/SF/mo5 buildings
- NNN$1.25–$3.50/SF/mo5 buildings
- Gross + Utilities & Janitorial$1.75/SF/mo1 building
4 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms6
- 3–4 rooms18
- 5–7 rooms4
- 8–12 rooms4
- 13+ rooms1
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B11
- Class C4
Hospitals within 5 miles
- Kaiser Foundation Hospital - San Diego, San Diego2.4 mi
- Grossmont Hospital, La Mesa3.8 mi
- Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa1.7 mi
Straight-line miles from the center of the College Area buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 6386 Alvarado Ct Alvarado Court Medical Bldg | B | 1982 | 15,487 SF6 spaces
| 4,442 SF | ~7–11 rooms | $2.35/SF/mo Modified Gross | |
| 5555 Reservoir Dr Alvarado Plaza I | B | 1979 | 10,158 SF5 spaces
| 3,369 SF | ~5–8 rooms | Withheld ask us | |
| 6411-6535 University Ave Rolando Plaza | B | 1975 | 9,303 SF1 space
| 9,303 SF | ~15–24 rooms | $2.00/SF/mo NNN | |
| 4660 El Cajon Blvd Asia Business Center | B | 2000 | 7,260 SF3 spaces
| 3,115 SF | ~5–8 rooms | $1.25–$2.50/SF/mo NNN | |
| 4275 El Cajon Blvd | B | 1946 | 5,700 SF1 space
| 5,700 SF | ~9–14 rooms | $2.35/SF/mo Modified Gross | |
| 6719 Alvarado Rd | B | 1991 | 5,602 SF3 spaces
| 2,967 SF | ~4–7 rooms | Withheld ask us | |
| 6310 Alvarado Ct Alvarado Research and Professional Center | C | 1975 | 4,205 SF1 space
| 4,205 SF | ~7–10 rooms | $2.35/SF/mo NNN | |
| 6505 Alvarado Rd Alvarado Research and Professional Center | B | 1966 | 3,997 SF3 spaces
| 2,113 SF | ~3–5 rooms | $2.35/SF/mo Modified Gross | |
| 6699 Alvarado Rd Alvarado Plaza II | B | 1982 | 3,072 SF2 spaces
| 1,724 SF | ~2–4 rooms | Withheld ask us | |
| 6475 Alvarado Rd Alvarado Research and Professional Center | B | 1960 | 2,733 SF2 spaces
| 1,957 SF | ~3–5 rooms | $2.35/SF/mo Modified Gross | |
| 4527-4541 College Ave College Avenue Professional Building | B | 1957 | 2,665 SF2 spaces
| 1,400 SF | ~2–3 rooms | $2.10/SF/mo NNN | |
| 4305 University Ave City Heights Center | B | 2003 | 2,019 SF1 space
| 2,019 SF | ~3–5 rooms | Withheld ask us | |
| 6367 Alvarado Ct Alvarado Medical Office Bldg | C | 1970 | 1,140 SF1 space
| 1,140 SF | ~1–2 rooms | $2.35/SF/mo Modified Gross | |
| 5059-5069 El Cajon Blvd | C | 1959 | 1,100 SF1 space
| 1,100 SF | ~1–2 rooms | $3.50/SF/mo NNN | |
| 5106 Federal Blvd | C | 1975 | 1,012 SF1 space
| 1,012 SF | ~1–2 rooms | $1.75/SF/mo Gross + Utilities & Janitorial |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| College Area | 15 | 75,453 SF | Modified Gross $2.35 (5) · NNN $1.25–$3.50 (5) · Gross + Utilities & Janitorial $1.75 (1) |
| Mission Valley | 13 | 99,719 SF | Gross + Electric $1.75–$2.65 (3) · Full Service $2.15–$2.90 (2) · Gross + Utilities $2.95 (2) |
| East County | 17 | 59,332 SF | NNN $1.80–$2.75 (6) · Modified Gross $1.50–$4.15 (4) · Gross + Utilities $2.95–$4.54 (2) |
| Kearny Mesa | 17 | 144,490 SF | Modified Gross $1.60–$3.50 (4) · NNN $2.75 (4) · Full Service $3.35 (1) |
| San Diego overall | 246 | 2,136,242 SF | NNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in College Area
How many medical office buildings have space available in College Area?
College Area has 15 buildings with medical office space available as of September 2026: 75,453 SF across 33 listed spaces. Of that, 55,090 SF is marked vacant now, and the largest single space is 9,303 SF, about 15 to 24 exam rooms.
What do medical office leases cost in College Area?
In College Area, 11 buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Modified Gross in four, Class B on NNN in three and Class C on NNN in two. Another four buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in College Area?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In College Area, the listed spaces break down as 6 for 1 to 2 rooms, 18 for 3 to 4, 4 for 5 to 7, 4 for 8 to 12 and 1 for 13 or more.
Which hospitals are near College Area?
Kaiser Foundation Hospital - San Diego is the closest hospital, 2.4 miles from the center of the College Area trade area. Also within 5 miles: Grossmont Hospital, La Mesa, 3.8 miles; Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa, 1.7 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the College Area availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in College Area
Send your size and timing. Live availability comes back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.
Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
- Lighthouse Pediatrics4,261 SFTorrance
- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine