Medical office space · data as of September 2026
Medical office space for lease in Kearny Mesa
17 buildings with 144,490 SF of medical space available across 56 listed spaces. 11 buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Kearny Mesa sits in the middle of San Diego's hospital map. Sharp Memorial and Rady Children's sit on adjacent campuses near Frost Street at the south end of the neighborhood, and Kaiser Permanente's San Diego Medical Center opened on Clairemont Mesa Boulevard in 2017. That concentration keeps referral traffic, imaging and lab services close, which is why specialists who want to be near those campuses without paying hospital-campus rents look here first.
Most of the medical-capable inventory is older one- and two-story Class B and C buildings along Clairemont Mesa Boulevard, Convoy, Ruffin and the Aero Drive corridor. Surface parking is usually easier than in Mission Valley or Hillcrest, and freeway access from 163, 805, 52 and 15 lets a practice draw patients from across the county.
What to watch: many of these buildings were built as general office, so check plumbing, ADA restrooms and HVAC before assuming a suite is ready for exam rooms. Landlords here quote a wide mix of lease structures, from Modified Gross to NNN, so compare total occupancy cost rather than the headline rate.
Kearny Mesa at a glance
- Buildings
- 17
- Medical space available
- 144,490 SF
- Vacant now
- 120,668 SF
- Largest single space
- 13,164 SF
Asking rents by lease structure
- Modified Gross$1.60–$3.50/SF/mo4 buildings
- NNN$2.75/SF/mo4 buildings
- Full Service$3.35/SF/mo1 building
- Gross + Electric$2.40–$2.50/SF/mo1 building
- Gross + Utilities$1.95/SF/mo1 building
6 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms23
- 3–4 rooms16
- 5–7 rooms9
- 8–12 rooms3
- 13+ rooms5
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B11
- Class C6
Hospitals within 5 miles
- Sharp Memorial Hospital, San Diego1.6 mi
- Rady Children's Hospital - San Diego (children's), San Diego1.6 mi
- Kaiser Foundation Hospital - San Diego, San Diego3.4 mi
- UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego4.8 mi
- Scripps Mercy Hospital, San Diego4.9 mi
Straight-line miles from the center of the Kearny Mesa buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 3760 Convoy St Bldg 2 | B | 1984 | 35,161 SF9 spaces
| 13,164 SF | ~21–34 rooms | Withheld ask us | |
| 3444 Kearny Villa Rd Coast Medical Center | B | 1985 | 33,645 SF6 spaces
| 10,252 SF | ~17–26 rooms | Withheld ask us | |
| 9610 Granite Ridge Dr | B | 1991 | 25,680 SF3 spaces
| 12,114 SF | ~20–31 rooms | $2.95/SF/mo Modified Gross | |
| 3750 Convoy St | B | 1984 | 7,891 SF4 spaces
| 3,227 SF | ~5–8 rooms | Withheld ask us | |
| 7071 Convoy Ct Convoy Business Center | B | 1973 | 7,812 SF4 spaces
| 2,491 SF | ~4–6 rooms | $1.95/SF/mo Gross + Utilities | |
| 8334 Clairemont Mesa Blvd | C | 1975 | 6,643 SF7 spaces
| 1,857 SF | ~3–4 rooms | $2.75/SF/mo NNN | |
| 8322 Clairemont Mesa Blvd | C | 1975 | 4,444 SF4 spaces
| 1,662 SF | ~2–4 rooms | $2.75/SF/mo NNN | |
| 8304 Clairemont Mesa Blvd | C | 1975 | 3,857 SF4 spaces
| 1,113 SF | ~1–2 rooms | $2.75/SF/mo NNN | |
| 9373 Hazard Way | B | 1980 | 3,790 SF2 spaces
| 2,250 SF | ~3–5 rooms | $3.50/SF/mo Modified Gross | |
| 4542 Ruffner St Square One Office Plaza | B | 1983 | 3,628 SF1 space
| 3,628 SF | ~6–9 rooms | $2.40–$2.50/SF/mo Gross + Electric | |
| 8010 Frost St Frost Street Medical Center | C | 1988 | 3,197 SF2 spaces
| 1,779 SF | ~2–4 rooms | Withheld ask us | |
| 8340 Clairemont Mesa Blvd | C | 1975 | 2,734 SF5 spaces
| 642 SF | ~1 room | $2.75/SF/mo NNN | |
| 8008 Frost St Frost Street Medical Center | C | 1982 | 1,612 SF1 space
| 1,612 SF | ~2–4 rooms | Withheld ask us | |
| 3645 Ruffin Rd Ruffin Business Center | B | 1986 | 1,339 SF1 space
| 1,339 SF | ~2–3 rooms | Withheld ask us | |
| 5575 Ruffin Rd | B | 1987 | 1,313 SF1 space
| 1,313 SF | ~2–3 rooms | $3.35/SF/mo Full Service | |
| 9245 Sky Park Ct | B | 1986 | 984 SF1 space
| 984 SF | ~1–2 rooms | $2.35/SF/mo Modified Gross | |
| 7975 Raytheon Rd | B | 1989 | 760 SF1 space
| 760 SF | ~1 room | $1.60/SF/mo Modified Gross |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Kearny Mesa | 17 | 144,490 SF | Modified Gross $1.60–$3.50 (4) · NNN $2.75 (4) · Full Service $3.35 (1) |
| Mission Valley | 13 | 99,719 SF | Gross + Electric $1.75–$2.65 (3) · Full Service $2.15–$2.90 (2) · Gross + Utilities $2.95 (2) |
| Mira Mesa and Miramar | 7 | 326,272 SF | Gross + Utilities $2.25–$3.35 (2) · Gross + Utilities & Janitorial $1.65 (1) |
| Uptown, Bankers Hill and Downtown | 11 | 91,377 SF | Modified Gross $2.25–$3.65 (3) · NNN $1.95–$2.60 (3) · Gross + Utilities $2.35–$3.25 (1) |
| San Diego overall | 246 | 2,136,242 SF | NNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Trade area context
Sharp Rees-Stealy Kearny Mesa is open. Sharp reported on May 21, 2026 that its 98,000-square-foot medical office building at 8975 Balboa Avenue now consolidates the Genesee, Mira Mesa and Murphy Canyon sites. It adds to a cluster of hospital campuses within about 1.6 miles of the center of the trade area.
- 78,290 residents in the ZIP areas, 14.6% of them 65 or older, 95.3% insured. Median household income runs from $99,644 (92111) to $132,534 (92123).
- Sharp Memorial and Rady Children's are adjacent campuses near Frost Street, each 1.60 miles from the center of the trade area. Kaiser Permanente San Diego Medical Center is 1.16 miles.
- Clairemont Mesa Boulevard counts 19,704 to 59,469 vehicles a day near listed buildings, and Balboa Avenue 19,788 to 50,315 (CoStar, 2026 counts).
- Frost Street counts 6,416, so the hospital blocks and the busy corridors are not the same place.
The lease read: visibility is available on Clairemont Mesa and Balboa. Near the hospital campuses, ask how patients find the suite and where they park. A great address on a quiet street is still a quiet street.
Short version: a newly consolidated Sharp building, three hospital campuses 1.16 to 1.60 miles out, and busy corridors that sit apart from them. Which of those campuses do your referrals run to today?
Sources: Census Bureau ACS 2020-2024 5-year; CMS Hospital General Information; CoStar traffic count reports (October 2026). Sharp HealthCare newsroom (May 21, 2026). ZIP areas extend beyond the neighborhood.
Questions about the Kearny Mesa trade area
Which hospitals are near the Kearny Mesa trade area?
Sharp Memorial Hospital and Rady Children's Hospital are adjacent campuses near Frost Street, each 1.60 miles from the trade area center. Kaiser Permanente San Diego Medical Center on Ruffin Road is 1.16 miles, and Sharp Mesa Vista Hospital, a psychiatric hospital, is 1.93 miles.
What is new in the Kearny Mesa trade area?
Sharp HealthCare reported on May 21, 2026 that Sharp Rees-Stealy Kearny Mesa is open at 8975 Balboa Avenue, a 98,000-square-foot medical office building that consolidates the Genesee, Mira Mesa and Murphy Canyon sites.
How many residents have Medicaid or military coverage?
Medicaid or other means-tested coverage alone covers 14.9% of residents, and TRICARE or military coverage reaches 7.3%, alone or combined with other coverage (ACS 2020-2024 5-year, two ZIP areas combined).
Questions about medical office space in Kearny Mesa
How many medical office buildings have space available in Kearny Mesa?
Kearny Mesa has 17 buildings with medical office space available as of September 2026: 144,490 SF across 56 listed spaces. Of that, 120,668 SF is marked vacant now, and the largest single space is 13,164 SF, about 21 to 34 exam rooms.
What do medical office leases cost in Kearny Mesa?
In Kearny Mesa, 11 buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Modified Gross in four, Class C on NNN in four and Class B on Full Service in one. Across Central San Diego, Class B buildings on Modified Gross ask a median $2.35/SF/month. Another six buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Kearny Mesa?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Kearny Mesa, the listed spaces break down as 23 for 1 to 2 rooms, 16 for 3 to 4, 9 for 5 to 7, 3 for 8 to 12 and 5 for 13 or more.
Which hospitals are near Kearny Mesa?
Sharp Memorial Hospital is the closest hospital, 1.6 miles from the center of the Kearny Mesa trade area. Also within 5 miles: Rady Children's Hospital - San Diego (children's), San Diego, 1.6 miles; Kaiser Foundation Hospital - San Diego, San Diego, 3.4 miles; UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego, 4.8 miles; Scripps Mercy Hospital, San Diego, 4.9 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Kearny Mesa availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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