Medical office space · data as of September 2026
Medical office space for lease in Pasadena
30 buildings with 211,174 SF of medical space available across 66 listed spaces. The largest like group, six Class B buildings on Full Service, asks a median $3.12/SF/month.
Huntington Hospital sits 0.7 mile from the center of the Pasadena trade area.
That's straight-line distance from the middle of 30 buildings, so individual buildings sit closer or farther. Across the trade area, the largest like group, six Class B buildings on Full Service, asks a median $3.12/SF/month, and six post no asking rent. Of the 30 buildings, 8 sit on Fair Oaks Ave, Raymond Ave and Arroyo Pky.
One more fact changes the read. Nearby, Class B buildings on NNN in Eastern San Gabriel Valley ask a median $2.50/SF/month, against $3.95 here. The lease read: a priced alternative across the trade area line, in a building of the same class, changes how a landlord answers. It's the cheapest leverage there is.
Short version: Huntington Hospital sits 0.7 mile out, and matched Class B NNN buildings in Eastern San Gabriel Valley nearby ask $1.45 less at the median. The comparison that moves a landlord is the one across the line. If the right suite turned up in Eastern San Gabriel Valley, would your practice take it?
Pasadena at a glance
- Buildings
- 30
- Medical space available
- 211,174 SF
- Vacant now
- 140,290 SF
- Largest single space
- 19,860 SF
Asking rents by lease structure
- Full Service$2.25–$4.35/SF/mo8 buildings
- NNN$2.75–$5.75/SF/mo8 buildings
- Modified Gross$2.42–$4.15/SF/mo6 buildings
- Gross + Utilities$5.50/SF/mo1 building
- Lease type not stated$2.40–$2.80/SF/mo1 building
6 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms15
- 3–4 rooms26
- 5–7 rooms10
- 8–12 rooms8
- 13+ rooms6
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B22
- Class C8
Hospitals within 5 miles
- Huntington Hospital, Pasadena0.7 mi
- San Gabriel Valley Medical Center, San Gabriel3.6 mi
- Alhambra Hospital Medical Center, Alhambra3.6 mi
- Glendale Adventist Medical Center, Glendale4.8 mi
- Aurora Las Encinas (psychiatric), Pasadena3.1 mi
Straight-line miles from the center of the Pasadena buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 350 W Colorado Blvd | B | 1985 | 48,781 SF4 spaces
| 19,860 SF | ~33–51 rooms | Withheld ask us | |
| 66 Hurlbut St | B | 1982 | 21,242 SF3 spaces
| 8,889 SF | ~14–23 rooms | $4.00/SF/mo NNN | |
| 625 Fair Oaks Ave | B | 1987 | 17,396 SF4 spaces
| 7,721 SF | ~12–20 rooms | $2.99/SF/mo Full Service | |
| 630 S Raymond Ave Pasadena Medical | B | 2007 | 13,742 SF5 spaces
| 4,282 SF | ~7–11 rooms | Withheld ask us | |
| 50 Bellefontaine St Cotton Medical Center North | B | 1975 | 13,662 SF4 spaces
| 6,688 SF | ~11–17 rooms | Withheld ask us | |
| 401 S Fair Oaks Ave | C | 1973 | 12,426 SF1 space
| 12,426 SF | ~20–32 rooms | $4.00/SF/mo NNN | |
| 800 Fairmount Ave Huntington Medical Plaza Offices | B | 1984 | 11,244 SF5 spaces
| 4,609 SF | ~7–11 rooms | $3.95/SF/mo Modified Gross | |
| 960 E Green St Thatcher Medical Bldg | B | 1963 | 8,998 SF7 spaces
| 2,301 SF | ~3–5 rooms | $3.15–$4.15/SF/mo Full Service | |
| 650 S Raymond Ave | B | 1965 | 7,000 SF1 space
| 7,000 SF | ~11–18 rooms | $3.95/SF/mo NNN | |
| 55 E California Blvd California Medical Bldg | B | 1983 | 5,606 SF3 spaces
| 2,056 SF | ~3–5 rooms | Withheld ask us | |
| 65 N Madison Ave Pasadena Medical Bldg | C | 1925 | 5,450 SF4 spaces
| 2,143 SF | ~3–5 rooms | $3.75/SF/mo Full Service | |
| 959 E Walnut St | B | 1977 | 5,140 SF3 spaces
| 3,123 SF | ~5–8 rooms | $2.50/SF/mo Full Service | |
| 10 Congress St Pasadena Medical Plaza | C | 1972 | 5,030 SF3 spaces
| 2,158 SF | ~3–5 rooms | $4.35/SF/mo Full Service | |
| 150 N Orange Grove Blvd | B | 1981 | 5,000 SF1 space
| 5,000 SF | ~8–12 rooms | $5.75/SF/mo NNN | |
| 50 N Hill Ave | B | 1984 | 4,945 SF2 spaces
| 3,211 SF | ~5–8 rooms | $2.40–$2.80/SF/mo | |
| 797 Fair Oaks Ave Outpatient Surgery Center | C | 1985 | 4,082 SF1 space
| 4,082 SF | ~6–10 rooms | $4.15/SF/mo Modified Gross | |
| 950 S Arroyo Pky | B | 1981 | 2,812 SF1 space
| 2,812 SF | ~4–7 rooms | $3.50/SF/mo NNN | |
| 1968 Lake Ave Millard Place | B | 2015 | 2,261 SF2 spaces
| 1,135 SF | ~1–2 rooms | $2.60/SF/mo Modified Gross | |
| 299 N Euclid Ave | B | 1982 | 2,153 SF1 space
| 2,153 SF | ~3–5 rooms | $3.25/SF/mo Full Service | |
| 217 S Fair Oaks Ave | C | 1922 | 2,050 SF1 space
| 2,050 SF | ~3–5 rooms | $4.95/SF/mo NNN | |
| 50 Alessandro Pl Cotton Medical Center South | B | 1983 | 1,906 SF1 space
| 1,906 SF | ~3–4 rooms | Withheld ask us | |
| 675 S Arroyo Pky Arroyo Medical Plaza | B | 1987 | 1,584 SF1 space
| 1,584 SF | ~2–4 rooms | $3.50/SF/mo Full Service | |
| 221-249 S Euclid Ave Building 2 | C | 1978 | 1,420 SF1 space
| 1,420 SF | ~2–3 rooms | $2.42/SF/mo Modified Gross | |
| 740-750 E Green St | B | 1963 | 1,375 SF1 space
| 1,375 SF | ~2–3 rooms | $2.25/SF/mo Full Service | |
| 1341-1349 Foothill Blvd, Ln | B | 1953 | 1,200 SF1 space
| 1,200 SF | ~2–3 rooms | $5.50/SF/mo Gross + Utilities | |
| 7232 Rosemead Blvd Huntington Plaza | B | 2017 | 1,162 SF1 space
| 1,162 SF | ~1–3 rooms | $2.75/SF/mo NNN | |
| 1932-1936 Huntington Dr | B | 1962 | 1,075 SF1 space
| 1,075 SF | ~1–2 rooms | $3.50/SF/mo Modified Gross | |
| 1344 Granada Ave | C | 1949 | 1,022 SF1 space
| 1,022 SF | ~1–2 rooms | $4.00/SF/mo Modified Gross | |
| 4515 Castle Rd | C | 1957 | 710 SF1 space
| 710 SF | ~1 room | $4.00/SF/mo NNN | |
| 2810 E Del Mar Blvd | B | 1989 | 700 SF1 space
| 700 SF | ~1 room | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Pasadena | 30 | 211,174 SF | Full Service $2.25–$4.35 (8) · NNN $2.75–$5.75 (8) · Modified Gross $2.42–$4.15 (6) |
| Glendale | 29 | 198,982 SF | Full Service $2.60–$4.10 (8) · NNN $1.75–$4.00 (4) · Modified Gross $2.95–$6.00 (3) |
| Western San Gabriel Valley | 48 | 281,394 SF | Modified Gross $1.50–$8.50 (17) · NNN $1.50–$3.40 (10) · Full Service $2.20–$3.60 (6) |
| Eastern San Gabriel Valley | 49 | 180,751 SF | NNN $1.28–$3.57 (16) · Modified Gross $1.50–$2.84 (15) · Full Service $1.15–$2.29 (6) |
| Los Angeles overall | 849 | 6,324,965 SF | Modified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Pasadena
How many medical office buildings have space available in Pasadena?
Pasadena has 30 buildings with medical office space available as of September 2026: 211,174 SF across 66 listed spaces. Of that, 140,290 SF is marked vacant now, and the largest single space is 19,860 SF, about 33 to 51 exam rooms.
What do medical office leases cost in Pasadena?
In Pasadena, Class B buildings on Full Service ask $2.25 to $3.65/SF/month, with a median of $3.12, across six buildings built from 1963 to 1987. Class B on NNN: $2.75 to $5.75, median $3.95, across five buildings built from 1965 to 2017. Each building counts once, at the middle of its published range. Across the Tri-Cities (Burbank, Glendale and Pasadena), Class B buildings on Full Service ask a median $3.10/SF/month. The remaining 13 priced buildings sit in classes and structures with fewer than five buildings each, too few to call typical. Another six buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Pasadena?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Pasadena, the listed spaces break down as 15 for 1 to 2 rooms, 26 for 3 to 4, 10 for 5 to 7, 8 for 8 to 12 and 6 for 13 or more.
Which hospitals are near Pasadena?
Huntington Hospital is the closest hospital, 0.7 mile from the center of the Pasadena trade area. Also within 5 miles: San Gabriel Valley Medical Center, San Gabriel, 3.6 miles; Alhambra Hospital Medical Center, Alhambra, 3.6 miles; Glendale Adventist Medical Center, Glendale, 4.8 miles; Aurora Las Encinas (psychiatric), Pasadena, 3.1 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Pasadena availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Pasadena
Send your size and timing. Live availability comes back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.
Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
- Lighthouse Pediatrics4,261 SFTorrance
- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine