Medical office space · data as of September 2026
Medical office space for lease in Laguna Hills and Aliso Viejo
17 buildings with 137,291 SF of medical space available across 59 listed spaces. Five buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Of the 17 buildings with medical space listed in Laguna Hills and Aliso Viejo this September, nine post no asking rent at all.
Only five publish a direct asking rent, mostly NNN, at $2.70 to $3.95/SF/month, and three more price sublease space only. The rest quote once a practice asks, which is standard and not a warning sign. It does mean a comparison built from listings is a comparison of five buildings out of 17.
Here's the part that gets less attention. Memorialcare Saddleback Medical Center is 0.6 mile from the center of the trade area. From the real estate side, a short distance to a campus is worth paying for only if it's the drive your practice actually makes. Pay for that, and negotiate everything else.
Short version: 9 of 17 buildings in Laguna Hills and Aliso Viejo post no rent, and Memorialcare Saddleback Medical Center sits 0.6 mile out. Pay for the distance that matters and negotiate the rest. How often does your practice make the trip to Memorialcare Saddleback Medical Center now?
Laguna Hills and Aliso Viejo at a glance
- Buildings
- 17
- Medical space available
- 137,291 SF
- Vacant now
- 125,034 SF
- Largest single space
- 12,101 SF
Asking rents by lease structure
- NNN$2.70–$3.95/SF/mo3 buildings
- Full Service$2.65–$2.75/SF/mo1 building
- Modified Gross$2.70/SF/mo1 building
9 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms11
- 3–4 rooms24
- 5–7 rooms14
- 8–12 rooms7
- 13+ rooms1
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class A3
- Class B14
Hospitals within 5 miles
- Memorialcare Saddleback Medical Center, Laguna Hills0.6 mi
- Providence Mission Hospital, Mission Viejo3.5 mi
- Children's Hospital at Mission (children's), Mission Viejo3.5 mi
Straight-line miles from the center of the Laguna Hills and Aliso Viejo buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 24422 Avenida De La Carlota Oakbrook Plaza | B | 1983 | 57,677 SF18 spaces
| 12,101 SF | ~20–31 rooms | Withheld ask us | |
| 23961 Calle de la Magdalena Saddleback Medical | A | 1980 | 21,127 SF8 spaces
| 5,377 SF | ~8–13 rooms | Withheld ask us | |
| 24361 El Toro Rd Town Centre Professional | B | 2001 | 10,015 SF4 spaces
| 2,734 SF | ~4–7 rooms | Withheld ask us | |
| 24012 Calle de la Plata Saddleback Professional Center | B | 1982 | 8,905 SF5 spaces
| 2,439 SF | ~4–6 rooms | Withheld ask us | |
| 24541 Pacific Park Dr Pacific Park Medical-Dental | B | 1991 | 8,238 SF4 spaces
| 2,127 SF | ~3–5 rooms | $2.70/SF/mo NNN | |
| 24022 Calle de la Plata The Laguna Building | B | 1983 | 5,836 SF3 spaces
| 2,292 SF | ~3–5 rooms | Withheld ask us | |
| 24799 Alicia Pky | B | 2013 | 4,327 SF1 space
| 4,327 SF | ~7–11 rooms | Withheld ask us | |
| 24953 Paseo De Valencia Bldg C | B | 1976 | 3,764 SF3 spaces
| 1,838 SF | ~3–4 rooms | $2.70/SF/mo Modified Gross | |
| 24953 Paseo De Valencia | B | 1977 | 2,882 SF4 spaces
| 880 SF | ~1–2 rooms | $2.65–$2.75/SF/mo Full Service | |
| 24401 Calle de la Louisa Saddleback Women's Health Pavillion | B | 2023 | 2,800 SF1 space
| 2,800 SF | ~4–7 rooms | Withheld ask us | |
| 25200 La Paz Rd South County Medical Center | B | 1979 | 2,654 SF1 space
| 2,654 SF | ~4–6 rooms | $3.25/SF/mo NNN | |
| 24100 El Toro Rd Valencia Center | B | 1974 | 2,585 SF1 space
| 2,585 SF | ~4–6 rooms | $3.15/SF/mo Gross + Electric & Janitorial · sublease | |
| 23521 Paseo de Valencia Taj Mahal Medical Center | A | 1964 | 2,485 SF2 spaces
| 1,556 SF | ~2–4 rooms | Withheld ask us | |
| 2 Journey 2 Journey Medical Plaza | B | 2012 | 1,429 SF1 space
| 1,429 SF | ~2–3 rooms | $3.95/SF/mo NNN | |
| 24411 Health Center Dr MemorialCare Saddleback Medical Center | A | 1988 | 1,347 SF1 space
| 1,347 SF | ~2–3 rooms | $4.40/SF/mo Full Service · sublease | |
| 22912 Pacific Park Dr | B | 1999 | 1,100 SF1 space
| 1,100 SF | ~1–2 rooms | Withheld ask us | |
| 24953 Paseo De Valencia Bldg B | B | 1978 | 120 SF1 space
| 120 SF | $2.00/SF/mo Modified Gross · sublease |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Laguna Hills and Aliso Viejo | 17 | 137,291 SF | NNN $2.70–$3.95 (3) · Full Service $2.65–$2.75 (1) · Modified Gross $2.70 (1) |
| Mission Viejo | 19 | 181,823 SF | Full Service $1.50–$3.15 (3) · Modified Gross $3.00–$3.50 (2) · NNN $3.00–$3.30 (2) |
| Lake Forest and Foothill Ranch | 7 | 21,681 SF | Full Service $2.85 (1) · NNN $2.45 (1) |
| Irvine Spectrum | 12 | 102,527 SF | NNN $3.25–$4.75 (5) · Full Service $3.00 (1) |
| Orange County overall | 317 | 2,274,339 SF | NNN $1.15–$5.50 (67) · Modified Gross $1.25–$4.95 (49) · Full Service $1.25–$6.00 (47) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Laguna Hills and Aliso Viejo
How many medical office buildings have space available in Laguna Hills and Aliso Viejo?
Laguna Hills and Aliso Viejo has 17 buildings with medical office space available as of September 2026: 137,291 SF across 59 listed spaces. Of that, 125,034 SF is marked vacant now, and the largest single space is 12,101 SF, about 20 to 31 exam rooms.
What do medical office leases cost in Laguna Hills and Aliso Viejo?
In Laguna Hills and Aliso Viejo, five buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on NNN in three, Class B on Full Service in one and Class B on Modified Gross in one. Another nine buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Laguna Hills and Aliso Viejo?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Laguna Hills and Aliso Viejo, the listed spaces break down as 11 for 1 to 2 rooms, 24 for 3 to 4, 14 for 5 to 7, 7 for 8 to 12 and 1 for 13 or more.
Which hospitals are near Laguna Hills and Aliso Viejo?
Memorialcare Saddleback Medical Center is the closest hospital, 0.6 mile from the center of the Laguna Hills and Aliso Viejo trade area. Also within 5 miles: Providence Mission Hospital, Mission Viejo, 3.5 miles; Children's Hospital at Mission (children's), Mission Viejo, 3.5 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Laguna Hills and Aliso Viejo availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Laguna Hills and Aliso Viejo
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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