Medical office space · data as of September 2026
Medical office space for lease in Lake Forest and Foothill Ranch
7 buildings with 21,681 SF of medical space available across 16 listed spaces. Two buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Sublease space is listed in three of seven buildings with medical space in Lake Forest and Foothill Ranch this September.
A sublease is someone else's lease. The remaining term, the existing build-out and the landlord's consent all come with it, and the sublessor (the tenant leaving) sets the asking terms. Buildings that list only sublease space are left out of the rent ranges on this page for that reason. Here that's three buildings.
One more fact changes the read. Of the seven buildings, four post no asking rent. The lease read: get a number from every building worth a tour, posted or not, before you pick a favorite. A landlord who knows you're only comparing posted rents knows exactly who it's competing with. The asking rent is the landlord's starting position, not yours. Unposted rents leave negotiation up to tenant improvements.
So: three of seven buildings carry sublease space, and four of seven buildings in Lake Forest and Foothill Ranch post no rent. The numbers that matter here come on request. Of the buildings on your short list, how many have given you a number in writing?
Lake Forest and Foothill Ranch at a glance
- Buildings
- 7
- Medical space available
- 21,681 SF
- Vacant now
- 15,292 SF
- Largest single space
- 6,389 SF
Asking rents by lease structure
- Full Service$2.85/SF/mo1 building
- NNN$2.45/SF/mo1 building
4 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms4
- 3–4 rooms4
- 5–7 rooms0
- 8–12 rooms2
- 13+ rooms0
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B5
- Class C2
Hospitals within 5 miles
- Memorialcare Saddleback Medical Center, Laguna Hills2.3 mi
- Hoag Orthopedic Institute, Irvine4.8 mi
Straight-line miles from the center of the Lake Forest and Foothill Ranch buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 27462 Portola Pky Silhouette Medical Plaza | B | 2000 | 6,389 SF1 space
| 6,389 SF | ~10–16 rooms | Withheld ask us | |
| 23591 El Toro Rd | C | 1979 | 5,057 SF10 spaces
| 1,581 SF | ~2–4 rooms | $2.85/SF/mo Full Service | |
| 22855 Lake Forest Dr | C | 1990 | 4,500 SF1 space
| 4,500 SF | ~7–11 rooms | Withheld ask us | |
| 23101 Lake Center Dr Lake Forest Executive Center | B | 1985 | 1,732 SF1 space
| 1,732 SF | ~2–4 rooms | $2.50/SF/mo Full Service · sublease | |
| 23321 El Toro Rd | B | 1978 | 1,586 SF1 space
| 1,586 SF | ~2–4 rooms | $2.45/SF/mo NNN | |
| 26750 Towne Centre Dr Bldg B | B | 2005 | 1,417 SF1 space
| 1,417 SF | ~2–3 rooms | Withheld ask us | |
| 23832 Rockfield Blvd Rockfield Plaza | B | 1985 | 1,000 SF1 space
| 1,000 SF | ~1–2 rooms | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Lake Forest and Foothill Ranch | 7 | 21,681 SF | Full Service $2.85 (1) · NNN $2.45 (1) |
| Laguna Hills and Aliso Viejo | 17 | 137,291 SF | NNN $2.70–$3.95 (3) · Full Service $2.65–$2.75 (1) · Modified Gross $2.70 (1) |
| Irvine Spectrum | 12 | 102,527 SF | NNN $3.25–$4.75 (5) · Full Service $3.00 (1) |
| Mission Viejo | 19 | 181,823 SF | Full Service $1.50–$3.15 (3) · Modified Gross $3.00–$3.50 (2) · NNN $3.00–$3.30 (2) |
| Orange County overall | 317 | 2,274,339 SF | NNN $1.15–$5.50 (67) · Modified Gross $1.25–$4.95 (49) · Full Service $1.25–$6.00 (47) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Lake Forest and Foothill Ranch
How many medical office buildings have space available in Lake Forest and Foothill Ranch?
Lake Forest and Foothill Ranch has 7 buildings with medical office space available as of September 2026: 21,681 SF across 16 listed spaces. Of that, 15,292 SF is marked vacant now, and the largest single space is 6,389 SF, about 10 to 16 exam rooms.
What do medical office leases cost in Lake Forest and Foothill Ranch?
In Lake Forest and Foothill Ranch, two buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class C on Full Service in one and Class B on NNN in one. Another four buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Lake Forest and Foothill Ranch?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Lake Forest and Foothill Ranch, the listed spaces break down as 4 for 1 to 2 rooms, 4 for 3 to 4 and 2 for 8 to 12.
Which hospitals are near Lake Forest and Foothill Ranch?
Memorialcare Saddleback Medical Center is the closest hospital, 2.3 miles from the center of the Lake Forest and Foothill Ranch trade area. Also within 5 miles: Hoag Orthopedic Institute, Irvine, 4.8 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Lake Forest and Foothill Ranch availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Lake Forest and Foothill Ranch
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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