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Medical office space · data as of September 2026

Medical office space for lease in East Orange

9 buildings with 42,068 SF of medical space available across 12 listed spaces. Eight buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.

Of the 12 spaces listed in East Orange this September, only one is 4,200 SF or larger.

The math: eight exam rooms take roughly 3,080 to 4,800 rentable SF, at 385 to 600 SF a room. Here, three listed spaces suit one or two rooms, eight fit three to seven, and the largest single space is 19,367 SF, about 32 to 50 rooms.

The second thing to know is about location. Providence St. Joseph Hospital is 1.1 miles from the center of the trade area, and Children's Hospital of Orange County is 1.2 miles. From the real estate side, a short distance to a campus is worth paying for only if it's the drive your practice actually makes. Pay for that, and negotiate everything else.

Short version: only 1 of 12 spaces is 4,200 SF or larger, and two hospitals sit within 1.2 miles of the center. The address is fixed the day you sign; almost everything else is negotiable. How far is your current office from the campus you use most?

East Orange at a glance

Buildings
9
Medical space available
42,068 SF
Vacant now
35,646 SF
Largest single space
19,367 SF

Asking rents by lease structure

  • Modified Gross$2.40–$4.00/SF/mo4 buildings
  • Full Service$1.50–$2.49/SF/mo1 building
  • Gross + Electric$2.00/SF/mo1 building
  • NNN$3.90/SF/mo1 building
  • Lease type not stated$1.95/SF/mo1 building

1 building withholds pricing or doesn't publish it. Those numbers come from the landlords on request.

Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.

Available spaces by size

  • 1–2 rooms3
  • 3–4 rooms4
  • 5–7 rooms4
  • 8–12 rooms0
  • 13+ rooms1

Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.

Building class

  • Class B7
  • Class C2

Hospitals within 5 miles

  • Providence St. Joseph Hospital, Orange1.1 mi
  • Children's Hospital of Orange County (children's), Orange1.2 mi
  • Healthbridge Children's Hospital - Orange (children's), Orange1.3 mi
  • Chapman Global Medical Center, Orange1.6 mi
  • UCI Health-Orange, Orange2.2 mi

Straight-line miles from the center of the East Orange buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.

Buildings with medical space available

BuildingClassBuiltMedical spaceLargest spaceFitsAsking rent
280 S Main St
Main Street Medical Campus II
B200219,367 SF
1 space
  • Floor 2 · 5,000 to 19,367 SF · available now
19,367 SF~32–50 roomsWithheld
ask us
303 W Katella Ave
US Bank Bldg
B19786,521 SF
4 spaces
  • Suite 201 · 3,425 SF · available now
  • Suite 204 · 1,720 SF · available now
  • Suite 203 · 688 SF · available now
  • Suite 203 · 688 SF · available now
3,425 SF~5–8 rooms$1.95/SF/mo
725 W La Veta AveB19803,900 SF
1 space
  • Suite 210-B · 3,900 SF · available now
3,900 SF~6–10 rooms$4.00/SF/mo
Modified Gross
1018-1046 N Tustin St
El Patio
C19652,685 SF
1 space
  • Suite 1024 · 1,500 to 2,685 SF · available in 30 days
2,685 SF~4–6 rooms$2.00/SF/mo
Gross + Electric
3111 N Tustin AveB19882,617 SF
1 space
  • Suite 245 · 2,617 SF · available now
2,617 SF~4–6 rooms$1.50–$2.49/SF/mo
Full Service
805 W La Veta AveB19782,300 SF
1 space
  • Suite 207 · 2,300 SF · available now
2,300 SF~3–5 rooms$4.00/SF/mo
Modified Gross
1310 W Stewart Dr
Providence Building
B19831,968 SF
1 space
  • Suite 307 · 1,968 SF · available in 30 days
1,968 SF~3–5 rooms$3.90/SF/mo
NNN
172 N Tustin St
Courtyard Professional Office Bldg
C19631,769 SF
1 space
  • Suite 104 · 1,769 SF · available Oct 2026
1,769 SF~2–4 rooms$2.40–$3.10/SF/mo
Modified Gross
705 W La Veta AveB1979941 SF
1 space
  • Suite 114 · 941 SF · available now
941 SF~1–2 rooms$4.00/SF/mo
Modified Gross

Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.

Compared to nearby

AreaBuildingsMedical spacePublished asking rents ($/SF/mo, buildings)
East Orange942,068 SFModified Gross $2.40–$4.00 (4) · Full Service $1.50–$2.49 (1) · Gross + Electric $2.00 (1)
Anaheim Stadium Area551,197 SFFull Service $1.85–$2.05 (2) · Modified Gross $1.90–$1.95 (1) · NNN $2.65 (1)
Main Place12191,265 SFFull Service $1.96 (1) · NNN $3.00 (1)
Anaheim Hills523,825 SFNNN $2.05–$3.50 (3) · Full Service $2.25 (1)
Orange County overall3172,274,339 SFNNN $1.15–$5.50 (67) · Modified Gross $1.25–$4.95 (49) · Full Service $1.25–$6.00 (47)

Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.

Questions about medical office space in East Orange

How many medical office buildings have space available in East Orange?

East Orange has 9 buildings with medical office space available as of September 2026: 42,068 SF across 12 listed spaces. Of that, 35,646 SF is marked vacant now, and the largest single space is 19,367 SF, about 32 to 50 exam rooms.

What do medical office leases cost in East Orange?

In East Orange, seven buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on Modified Gross in three, Class B on Full Service in one and Class C on Gross + Electric in one. Another one building posts no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.

How much space does a medical practice need in East Orange?

About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In East Orange, the listed spaces break down as 3 for 1 to 2 rooms, 4 for 3 to 4, 4 for 5 to 7 and 1 for 13 or more.

Which hospitals are near East Orange?

Providence St. Joseph Hospital is the closest hospital, 1.1 miles from the center of the East Orange trade area. Also within 5 miles: Children's Hospital of Orange County (children's), Orange, 1.2 miles; Healthbridge Children's Hospital - Orange (children's), Orange, 1.3 miles; Chapman Global Medical Center, Orange, 1.6 miles; UCI Health-Orange, Orange, 2.2 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.

How current is the East Orange availability?

It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.

Send me what fits in East Orange

Send your size and timing. Live availability comes back within one business day.

Sent.

We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Jamal Brown, Real Estate Broker

Your advisor

Jamal Brown

Real Estate Broker · CA DRE #01780052

Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.

(619) 796-3390

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