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Medical office space · data as of September 2026

Medical office space for lease in El Cajon and East County

13 buildings with 30,556 SF of medical space available across 19 listed spaces. Eight buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.

El Cajon and East County lists 19 medical spaces this September. Only one is 4,200 SF or larger.

At 385 to 600 rentable SF per exam room (the room plus its share of waiting, work areas and halls), 4,200 SF holds about 7 to 10 rooms. Most of what's listed here is smaller: nine spaces suit one or two rooms and eight fit three to seven. The largest single space is 4,454 SF, about 7 to 11 rooms.

Here's the part that gets less attention. Landlords here quote two lease structures: NNN in five buildings, at $1.80 to $2.70/SF/month, and Modified Gross in three buildings. From the real estate side, the structure is part of the price. On an NNN quote, taxes, insurance and common-area costs come on top, so ask for the operating expense history (what those costs actually ran) before setting it next to a Modified Gross number.

Put together: only 1 of 19 spaces is 4,200 SF or larger, and landlords there quote two lease structures. Comparing rates without converting structures compares labels. When you set a quote here next to your current rent, are you comparing the same structure?

El Cajon and East County at a glance

Buildings
13
Medical space available
30,556 SF
Vacant now
21,648 SF
Largest single space
4,454 SF

Asking rents by lease structure

  • NNN$1.80–$2.75/SF/mo5 buildings
  • Modified Gross$1.50–$2.50/SF/mo3 buildings

5 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.

Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.

Available spaces by size

  • 1–2 rooms9
  • 3–4 rooms6
  • 5–7 rooms2
  • 8–12 rooms1
  • 13+ rooms0

Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.

Building class

  • Class B7
  • Class C6

Hospitals within 5 miles

  • Grossmont Hospital, La Mesa2.7 mi
  • Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa4.8 mi

Straight-line miles from the center of the El Cajon and East County buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.

Buildings with medical space available

BuildingClassBuiltMedical spaceLargest spaceFitsAsking rent
1625 E Main St
The El Cajon Medical Center
B19838,139 SF
2 spaces
  • Suite 100 · 4,454 SF · available now
  • Suite 202 · 1,685 to 3,685 SF · available now
4,454 SF~7–11 rooms$2.65–$2.75/SF/mo
NNN
10225 Austin Dr
Rancho San Diego Medical Dental Plaza
C19884,978 SF
2 spaces
  • Suite 201 · 3,397 SF · available May 2027
  • Suite 206 · 1,581 SF · available in 30 days
3,397 SF~5–8 roomsWithheld
ask us
353 E Park Ave
Rosemond
B20073,901 SF
4 spaces
  • Suite 104 · 1,093 SF · available now
  • Suite 103 · 1,053 SF · available now
  • Suite 201 · 888 SF · available now
  • Suite 203 · 867 SF · available now
1,093 SF~1–2 rooms$1.50/SF/mo
Modified Gross
9535 Mission Gorge Rd
Mission Plaza
B19802,190 SF
1 space
  • Suite K/L · 2,190 SF · available Jan 2027
2,190 SF~3–5 roomsWithheld
ask us
1620 Alpine Blvd
Alpine Regional Center
B20042,189 SF
2 spaces
  • Suite 125 · 1,112 SF · available now
  • Suite 208 · 1,077 SF · available now
1,112 SF~1–2 roomsWithheld
ask us
3915 N Bonita StB20001,740 SF
1 space
  • Floor 1 · 1,740 SF · available in 60 days
1,740 SF~2–4 rooms$2.10/SF/mo
NNN
8760 Cuyamaca St
Santee Medical/Professional Center
B19831,685 SF
1 space
  • Suite 205 · 1,685 SF · available now
1,685 SF~2–4 rooms$1.80/SF/mo
NNN
10201 Mission Gorge Rd
Santee Professional Center
C19781,484 SF
1 space
  • Suite F/G · 1,484 SF · available now
1,484 SF~2–3 rooms$1.95–$2.25/SF/mo
NNN
7733 Palm St
Palm Plaza
B19751,200 SF
1 space
  • Suite 105 · 1,200 SF · available now
1,200 SF~2–3 roomsWithheld
ask us
7850-7860 Golden Ave
Golden Professional Center
C19521,100 SF
1 space
  • Suite 7854 · 1,100 SF · available now
1,100 SF~1–2 roomsWithheld
ask us
6280 Jackson Dr
Lake Murray Medical & Dental Center
C1962828 SF
1 space
  • Suite 7 · 828 SF · available now
828 SF~1–2 rooms$2.00/SF/mo
NNN
669-681 S Mollison Ave
Mollison Plaza
C1975765 SF
1 space
  • Suite 671 B-C · 765 SF · available now
765 SF~1 room$1.50–$2.50/SF/mo
Modified Gross
1150 Broadway
East San Diego Board of Realtors
C1989357 SF
1 space
  • Floor 1 · 357 SF · available now
357 SF$2.24/SF/mo
Modified Gross

Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.

Compared to nearby

AreaBuildingsMedical spacePublished asking rents ($/SF/mo, buildings)
El Cajon and East County1330,556 SFNNN $1.80–$2.75 (5) · Modified Gross $1.50–$2.50 (3)
College Area1575,453 SFModified Gross $2.35 (5) · NNN $1.25–$3.50 (5) · Gross + Utilities & Janitorial $1.75 (1)
Mission Valley1399,719 SFGross + Electric $1.75–$2.65 (3) · Full Service $2.15–$2.90 (2) · Gross + Utilities $2.95 (2)
Chula Vista1036,768 SFModified Gross $2.38–$3.15 (3) · Gross + Electric $2.75 (1) · Lease type not stated $3.20 (1)
San Diego overall2462,136,242 SFNNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13)

Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.

Questions about medical office space in El Cajon and East County

How many medical office buildings have space available in El Cajon and East County?

El Cajon and East County has 13 buildings with medical office space available as of September 2026: 30,556 SF across 19 listed spaces. Of that, 21,648 SF is marked vacant now, and the largest single space is 4,454 SF, about 7 to 11 exam rooms.

What do medical office leases cost in El Cajon and East County?

In El Cajon and East County, eight buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on NNN in three, Class C on Modified Gross in two and Class C on NNN in two. Another five buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.

How much space does a medical practice need in El Cajon and East County?

About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In El Cajon and East County, the listed spaces break down as 9 for 1 to 2 rooms, 6 for 3 to 4, 2 for 5 to 7 and 1 for 8 to 12.

Which hospitals are near El Cajon and East County?

Grossmont Hospital is the closest hospital, 2.7 miles from the center of the El Cajon and East County trade area. Also within 5 miles: Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa, 4.8 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.

How current is the El Cajon and East County availability?

It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.

Send me what fits in El Cajon and East County

Send your size and timing. Live availability comes back within one business day.

Sent.

We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Jamal Brown, Real Estate Broker

Your advisor

Jamal Brown

Real Estate Broker · CA DRE #01780052

Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.

(619) 796-3390

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