Medical office space · data as of September 2026
399 E Highland Ave, San Bernardino St. Bernardine Medical Plaza (A)
30 medical office spaces listed, 55,044 SF in all, largest 6,510 SF (about 10 to 16 exam rooms). Of those, 30 are vacant now. The landlord quotes rent on request.
Listed spaces at 399 E Highland Ave
| Space | Use | Term |
|---|---|---|
| Suite 110 · 2,656 SF · available now | Office/Medical | Negotiable |
| Suite 100 · 1,425 SF · available now | Office/Medical | Negotiable |
| Suite 209 · 3,712 SF · available now | Office/Medical | Negotiable |
| Suite 220 · 2,284 SF · available now | Office/Medical | Negotiable |
| Suite 201 · 2,083 SF · available now | Office/Medical | Negotiable |
| Suite 212 · 1,686 SF · available now | Office/Medical | Negotiable |
| Suite 216 · 780 SF · available now | Office/Medical | Negotiable |
| Suite 214 · 620 SF · available now | Office/Medical | Negotiable |
| Suite 307 · 4,151 SF · available now | Office/Medical | Negotiable |
| Suite 316 · 2,311 SF · available now | Office/Medical | Negotiable |
| Suite 324 · 2,289 SF · available now | Office/Medical | Negotiable |
| Suite 310 · 1,689 SF · available now | Office/Medical | Negotiable |
| Suite 314 · 1,370 SF · available now | Office/Medical | Negotiable |
| Suite 329 · 1,187 SF · available now | Office/Medical | Negotiable |
| Suite 309 · 782 SF · available now | Office/Medical | Negotiable |
| Suite 409 · 6,510 SF · available now | Office/Medical | Negotiable |
| Suite 415 · 1,854 SF · available now | Office/Medical | Negotiable |
| Suite 424 · 1,389 SF · available now | Office/Medical | Negotiable |
| Suite 420 · 1,380 SF · available now | Office/Medical | Negotiable |
| Suite 418 · 1,315 SF · available now | Office/Medical | Negotiable |
| Suite 416 · 1,153 SF · available now | Office/Medical | Negotiable |
| Suite 503 · 1,958 SF · available now | Office/Medical | Negotiable |
| Suite 516 · 1,505 SF · available now | Office/Medical | Negotiable |
| Suite 524 · 1,451 SF · available now | Office/Medical | Negotiable |
| Suite 511 · 1,397 SF · available now | Office/Medical | Negotiable |
| Suite 502 · 1,345 SF · available now | Office/Medical | Negotiable |
| Suite 506 · 1,241 SF · available now | Office/Medical | Negotiable |
| Suite 517 · 1,234 SF · available now | Office/Medical | Negotiable |
| Suite 527 · 1,177 SF · available now | Office/Medical | Negotiable |
| Suite 523 · 1,110 SF · available now | Office/Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 55,044 SF
- Largest space
- 6,510 SF
- Fits
- ~10–16 rooms
- Vacant now
- 30 of 30
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In San Bernardino, 9 of 29 buildings do the same.
San Bernardino for comparison
- Modified Gross$1.45–$2.90/SF/mo10 buildings
- NNN$1.15–$2.25/SF/mo4 buildings
- Full Service$1.55–$2.00/SF/mo2 buildings
- Gross + Electric$1.50–$1.85/SF/mo1 building
- Gross + Utilities$1.53/SF/mo1 building
- Gross + Utilities & Janitorial$2.50/SF/mo1 building
- Lease type not stated$1.60–$1.68/SF/mo1 building
Lowest to highest published building asking rents in San Bernardino, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1971
- Stories5
- Rentable building area87,778 SF
- Parking ratio16.60 per 1,000 SF
- Leased37%
Hospitals near 399 E Highland Ave
- St. Bernardine Medical Center, San Bernardino0.1 mi
- Community Hospital of San Bernardino, San Bernardino2.6 mi
- Loma Linda University Medical Center, Loma Linda6.0 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in San Bernardino
- 401 E Highland Ave St. Bernardine Medical Plaza (B) 8,759 SF
- 2150 N Waterman Ave Waterman Medical Plaza 18,566 SF
- 2020 N Waterman De Leon Professional Building 2,891 SF · $1.65/SF/mo
- 1799 N Waterman Ave Waterman Professional Building 3,900 SF · $1.58–$1.60/SF/mo
See every building in the San Bernardino trade area guide.
Questions about 399 E Highland Ave
What medical office space is available at 399 E Highland Ave?
399 E Highland Ave in San Bernardino lists 30 medical office spaces, 55,044 SF in all, as of September 2026: Suite 110 · 2,656 SF · available now, Suite 100 · 1,425 SF · available now, Suite 209 · 3,712 SF · available now, Suite 220 · 2,284 SF · available now, Suite 201 · 2,083 SF · available now, Suite 212 · 1,686 SF · available now. Sizes are rentable square feet. Of those, 30 are vacant now.
What is the asking rent at 399 E Highland Ave?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 399 E Highland Ave?
About 10 to 16. The largest listed space is 6,510 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1971.
Which hospitals are near 399 E Highland Ave?
St. Bernardine Medical Center is the closest, 0.1 mile away. Also nearby: Community Hospital of San Bernardino, San Bernardino, 2.6 miles; Loma Linda University Medical Center, Loma Linda, 6.0 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 399 E Highland Ave current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 399 E Highland Ave
Send your size and timing. Live availability and terms for this building come back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.
Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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