Medical office space · data as of September 2026
3500 5th Ave, San Diego Webster Bldg
4 medical office spaces listed, 15,993 SF in all, largest 6,559 SF (about 10 to 17 exam rooms). Four of them are vacant now. Asking $2.60/SF/mo on a NNN basis.
Listed spaces at 3500 5th Ave
| Space | Use | Term |
|---|---|---|
| Suite 106 · 1,600 to 3,205 SF · available now | Medical | Negotiable |
| Suite 202 · 2,000 to 6,559 SF · available now | Office/Medical | Negotiable |
| Suite 203 · 2,282 SF · available now | Office/Medical | Negotiable |
| Suite 301 · 1,000 to 3,947 SF · available now | Office/Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 15,993 SF
- Largest space
- 6,559 SF
- Fits
- ~10–17 rooms
- Vacant now
- 4 of 4
Asking rent and building facts
Asking rent
- NNN$2.60/SF/mobuilding asking range
Uptown, Bankers Hill and Downtown for comparison
- Modified Gross$2.25–$3.65/SF/mo3 buildings
- NNN$1.95–$2.60/SF/mo3 buildings
- Gross + Utilities$2.35–$3.25/SF/mo1 building
Lowest to highest published building asking rents in Uptown, Bankers Hill and Downtown, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1971, renovated 1988
- Stories3
- Rentable building area32,563 SF
- Parking ratio3.00 per 1,000 SF
- Leased51%
Hospitals near 3500 5th Ave
- Scripps Mercy Hospital, San Diego0.7 mi
- UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego0.9 mi
- Nmc San Diego (military), San Diego1.5 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Uptown, Bankers Hill and Downtown
- 2918 5th Ave Fifth & Palm Building 5,182 SF · $3.65/SF/mo
- 3955-3995 5th Ave Village Hillcrest 2,862 SF
- 3935 1st Ave 4,000 SF · $2.25/SF/mo
- 3969 4th Ave 3,147 SF · $2.25/SF/mo
See every building in the Uptown, Bankers Hill and Downtown trade area guide.
Questions about 3500 5th Ave
What medical office space is available at 3500 5th Ave?
3500 5th Ave in San Diego lists 4 medical office spaces, 15,993 SF in all, as of September 2026: Suite 106 · 1,600 to 3,205 SF · available now, Suite 202 · 2,000 to 6,559 SF · available now, Suite 203 · 2,282 SF · available now, Suite 301 · 1,000 to 3,947 SF · available now. Sizes are rentable square feet. Of those, four are vacant now.
What is the asking rent at 3500 5th Ave?
$2.60/SF/mo, on a NNN basis, as published for this Class B building, built in 1971 (renovated 1988). Taxes, insurance and common-area costs come on top of an NNN rate.
How many exam rooms fit in the largest space at 3500 5th Ave?
About 10 to 17. The largest listed space is 6,559 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1971, renovated 1988.
Which hospitals are near 3500 5th Ave?
Scripps Mercy Hospital is the closest, 0.7 mile away. Also nearby: UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego, 0.9 mile; Nmc San Diego (military), San Diego, 1.5 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 3500 5th Ave current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 3500 5th Ave
Send your size and timing. Live availability and terms for this building come back within one business day.
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We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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