Medical office space · data as of September 2026
2131 3rd Ave, San Diego
1 medical office space listed, 1,905 SF in all, largest 1,905 SF (about 3 to 4 exam rooms). It's vacant now. The landlord quotes rent on request.
Listed spaces at 2131 3rd Ave
| Space | Use | Term |
|---|---|---|
| Floor 1 · 1,905 SF · available now | Office/Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 1,905 SF
- Largest space
- 1,905 SF
- Fits
- ~3–4 rooms
- Vacant now
- 1 of 1
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Uptown, Bankers Hill and Downtown, 4 of 11 buildings do the same.
Uptown, Bankers Hill and Downtown for comparison
- Modified Gross$2.25–$3.65/SF/mo3 buildings
- NNN$1.95–$2.60/SF/mo3 buildings
- Gross + Utilities$2.35–$3.25/SF/mo1 building
Lowest to highest published building asking rents in Uptown, Bankers Hill and Downtown, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass A
- Built1956, renovated 2018
- Stories4
- Rentable building area21,810 SF
- Parking ratio2.98 per 1,000 SF
- Leased91%
Hospitals near 2131 3rd Ave
- Nmc San Diego (military), San Diego1.0 mi
- Scripps Mercy Hospital, San Diego1.6 mi
- UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego1.8 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Uptown, Bankers Hill and Downtown
- 2918 5th Ave Fifth & Palm Building 5,182 SF · $3.65/SF/mo
- 450 A St 2,170 SF · $2.35–$3.25/SF/mo
- 3500 5th Ave Webster Bldg 15,993 SF · $2.60/SF/mo
- 3935 1st Ave 4,000 SF · $2.25/SF/mo
See every building in the Uptown, Bankers Hill and Downtown trade area guide.
Questions about 2131 3rd Ave
What medical office space is available at 2131 3rd Ave?
2131 3rd Ave in San Diego lists 1 medical office space, 1,905 SF in all, as of September 2026: Floor 1 · 1,905 SF · available now. Sizes are rentable square feet.
What is the asking rent at 2131 3rd Ave?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 2131 3rd Ave?
About 3 to 4. The largest listed space is 1,905 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1956, renovated 2018.
Which hospitals are near 2131 3rd Ave?
Nmc San Diego is the closest, 1 mile away. Also nearby: Scripps Mercy Hospital, San Diego, 1.6 miles; UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego, 1.8 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 2131 3rd Ave current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 2131 3rd Ave
Send your size and timing. Live availability and terms for this building come back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
- Lighthouse Pediatrics4,261 SFTorrance
- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine