Medical office space · data as of September 2026
Medical office space for lease in La Mesa
9 buildings with 38,155 SF of medical space available across 19 listed spaces. Four buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
La Mesa's medical market is built around Sharp Grossmont Hospital on Grossmont Center Drive, the largest hospital in East County. The blocks around the hospital and Grossmont Center hold medical office buildings, imaging and outpatient services, and practices that rely on hospital referrals or privileges tend to want to be within a few minutes of that campus. We have placed X-Ray Medical Group, Caring Physicians and Achilles Podiatry here.
Farther west, the Alvarado Road and Lake Murray Boulevard corridors near the San Diego city line offer smaller buildings, often at lower rents than the hospital campus. Interstate 8 and State Route 125 make the area reachable from El Cajon, Santee, Spring Valley and the College Area, and the Grossmont trolley station serves patients who do not drive.
Inventory is thin, so good suites do not sit long. Several landlords here withhold pricing or quote Gross plus utilities, which shifts electric and water costs to the tenant. Ask for the operating history before you sign, especially in older buildings.
La Mesa at a glance
- Buildings
- 9
- Medical space available
- 38,155 SF
- Vacant now
- 29,810 SF
- Largest single space
- 5,641 SF
Asking rents by lease structure
- Gross + Utilities$2.95–$4.54/SF/mo2 buildings
- Modified Gross$4.15/SF/mo1 building
- NNN$2.00/SF/mo1 building
5 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms5
- 3–4 rooms9
- 5–7 rooms2
- 8–12 rooms3
- 13+ rooms0
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class A1
- Class B7
- Class C1
Hospitals within 5 miles
- Grossmont Hospital, La Mesa0.3 mi
- Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa1.9 mi
Straight-line miles from the center of the La Mesa buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 8881 Fletcher Pky Fletcher Parkway Medical Center | B | 1985 | 9,559 SF4 spaces
| 5,125 SF | ~8–13 rooms | Withheld ask us | |
| 7777 Alvarado Rd Allied Plaza | A | 1983 | 8,699 SF4 spaces
| 4,351 SF | ~7–11 rooms | $2.95–$3.45/SF/mo Gross + Utilities | |
| 8851 Center Dr Grossmont Medical Office Building | B | 1986 | 5,641 SF1 space
| 5,641 SF | ~9–14 rooms | $2.00/SF/mo NNN | |
| 5565 Grossmont Center Dr | B | 1959 | 3,898 SF2 spaces
| 2,524 SF | ~4–6 rooms | Withheld ask us | |
| 8090 Parkway Dr | B | 1981 | 2,715 SF2 spaces
| 1,359 SF | ~2–3 rooms | $4.15/SF/mo Modified Gross | |
| 8690 Center Dr | C | 1997 | 2,700 SF1 space
| 2,700 SF | ~4–7 rooms | Withheld ask us | |
| 3835 Avocado Blvd Bldg B | B | 1982 | 2,425 SF2 spaces
| 1,381 SF | ~2–3 rooms | Withheld ask us | |
| 8911 La Mesa Blvd | B | 1989 | 1,638 SF2 spaces
| 880 SF | ~1–2 rooms | Withheld ask us | |
| 5200 Lake Murray Blvd | B | 1950 | 880 SF1 space
| 880 SF | ~1–2 rooms | $4.54/SF/mo Gross + Utilities |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| La Mesa | 9 | 38,155 SF | Gross + Utilities $2.95–$4.54 (2) · Modified Gross $4.15 (1) · NNN $2.00 (1) |
| Mission Valley | 13 | 99,719 SF | Gross + Electric $1.75–$2.65 (3) · Full Service $2.15–$2.90 (2) · Gross + Utilities $2.95 (2) |
| College Area | 15 | 75,453 SF | Modified Gross $2.35 (5) · NNN $1.25–$3.50 (5) · Gross + Utilities & Janitorial $1.75 (1) |
| Lemon Grv/Spring Vly | 2 | 2,300 SF | Withheld |
| San Diego overall | 246 | 2,136,242 SF | NNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Trade area context
Sharp Grossmont Hospital, which Sharp describes as the largest hospital in East County, is 0.35 mile from the center of the La Mesa trade area and 0.14 mile from the nearest listed building. Plenty of buildings here are a short walk from the main referral source.
- 74,642 residents in the ZIP areas, 17.2% of them 65 or older, 95.5% insured. 91941 is owner-majority (67.5%) and 91942 is renter-majority (54.5%).
- Sharp Grossmont has 562 beds on a campus with a cancer center, a heart and vascular center, a women's hospital and a surgery center, according to Sharp.
- Federal shortage designations for Medicaid-eligible primary care and dental reach ZIP 91941 through one census tract.
- Grossmont Center Drive counts 17,244 to 19,745 vehicles a day near listed buildings, La Mesa Boulevard 22,977 and Alvarado Road 3,078 (CoStar, 2026 counts).
The lease read: proximity is built in, visibility is not. Press on signage, parking and how far a patient walks from the car to your door. Alvarado Road at 3,078 will not advertise you. A good sign will.
Short version: a well-covered, mixed owner and renter base, a large hospital campus next door, and quieter streets at several doors. Do your patients find you through the hospital or through the street?
Sources: Census Bureau ACS 2020-2024 5-year; CMS Hospital General Information; CoStar traffic count reports (October 2026). HRSA shortage designation files (October 2026); Sharp HealthCare, sharp.com/locations/hospitals/sharp-grossmont (October 2026). ZIP areas extend beyond the city limits.
Questions about the La Mesa trade area
How close is Grossmont Hospital to the La Mesa trade area?
Grossmont Hospital (Sharp Grossmont) is 0.35 mile from the trade area center and 0.14 mile from the nearest listed building, and it has an emergency department (CMS Hospital General Information).
Is La Mesa a federally designated shortage area?
HRSA lists no whole-area designation covering either ZIP. Medicaid-eligible primary care and dental designations (El Cajon Central and South / Fletcher Hills) touch 91941 through one census tract, and the mental health designations covering La Mesa tracts are proposed for withdrawal.
What do incomes and housing look like by ZIP in La Mesa?
Median household income is $115,381 in 91941 and $92,896 in 91942. 91941 is 67.5% owner-occupied, while 91942 is 54.5% renter-occupied (ACS 2020-2024 5-year).
Questions about medical office space in La Mesa
How many medical office buildings have space available in La Mesa?
La Mesa has 9 buildings with medical office space available as of September 2026: 38,155 SF across 19 listed spaces. Of that, 29,810 SF is marked vacant now, and the largest single space is 5,641 SF, about 9 to 14 exam rooms.
What do medical office leases cost in La Mesa?
In La Mesa, four buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class A on Gross + Utilities in one, Class B on Gross + Utilities in one and Class B on Modified Gross in one. Another five buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in La Mesa?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In La Mesa, the listed spaces break down as 5 for 1 to 2 rooms, 9 for 3 to 4, 2 for 5 to 7 and 3 for 8 to 12.
Which hospitals are near La Mesa?
Grossmont Hospital is the closest hospital, 0.3 mile from the center of the La Mesa trade area. Also within 5 miles: Alvarado Parkway Institute Behavioral Health System (psychiatric), La Mesa, 1.9 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the La Mesa availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
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- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine