Medical office space · data as of September 2026
27462 Portola Pky, Foothill Ranch Silhouette Medical Plaza
1 medical office space listed, 6,389 SF in all, largest 6,389 SF (about 10 to 16 exam rooms). It isn't marked vacant now. The landlord quotes rent on request.
Listed spaces at 27462 Portola Pky
| Space | Use | Term |
|---|---|---|
| Suite 100 · 6,389 SF · available in 30 days | Office/Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 6,389 SF
- Largest space
- 6,389 SF
- Fits
- ~10–16 rooms
- Vacant now
- 0 of 1
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Lake Forest and Foothill Ranch, 4 of 7 buildings do the same.
Lake Forest and Foothill Ranch for comparison
- Full Service$2.85/SF/mo1 building
- NNN$2.45/SF/mo1 building
Lowest to highest published building asking rents in Lake Forest and Foothill Ranch, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built2000
- Stories2
- Rentable building area20,127 SF
- Parking ratio5.23 per 1,000 SF
- Leased100%
Hospitals near 27462 Portola Pky
- Memorialcare Saddleback Medical Center, Laguna Hills5.3 mi
- Hoag Orthopedic Institute, Irvine6.8 mi
- Providence Mission Hospital, Mission Viejo7.5 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Lake Forest and Foothill Ranch
- 26750 Towne Centre Dr Bldg B 1,417 SF
- 23321 El Toro Rd 1,586 SF · $2.45/SF/mo
- 23591 El Toro Rd 5,057 SF · $2.85/SF/mo
- 22855 Lake Forest Dr 4,500 SF
See every building in the Lake Forest and Foothill Ranch trade area guide.
Questions about 27462 Portola Pky
What medical office space is available at 27462 Portola Pky?
27462 Portola Pky in Foothill Ranch lists 1 medical office space, 6,389 SF in all, as of September 2026: Suite 100 · 6,389 SF · available in 30 days. Sizes are rentable square feet.
What is the asking rent at 27462 Portola Pky?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 27462 Portola Pky?
About 10 to 16. The largest listed space is 6,389 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 2000.
Which hospitals are near 27462 Portola Pky?
Memorialcare Saddleback Medical Center is the closest, 5.3 miles away. Also nearby: Hoag Orthopedic Institute, Irvine, 6.8 miles; Providence Mission Hospital, Mission Viejo, 7.5 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 27462 Portola Pky current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 27462 Portola Pky
Send your size and timing. Live availability and terms for this building come back within one business day.
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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