Medical office space · data as of September 2026
Medical office space for lease in Sorrento Mesa
5 buildings with 33,794 SF of medical space available across 12 listed spaces. Three buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Sorrento Mesa lists 12 medical spaces this September. Only one is 4,200 SF or larger.
At 385 to 600 rentable SF per exam room (the room plus its share of waiting, work areas and halls), 4,200 SF holds about 7 to 10 rooms. Most of what's listed here is smaller: one spaces suit one or two rooms and 10 fit three to seven. The largest single space is 6,548 SF, about 10 to 17 rooms.
The second thing to know is about location. Only five buildings list medical space here. From the real estate side, a thin trade area is where leverage gets made, not found. Price a credible alternative across the line before you negotiate, so the landlord is competing with something real.
Put together: only 1 of 12 spaces is 4,200 SF or larger, and Sorrento Mesa is a five-building trade area this September. A short list rewards the practice that brings its own alternative. Which trade area next to Sorrento Mesa would your practice consider if the right suite were there?
Sorrento Mesa at a glance
- Buildings
- 5
- Medical space available
- 33,794 SF
- Vacant now
- 30,381 SF
- Largest single space
- 6,548 SF
Asking rents by lease structure
- Gross + Electric & Janitorial$2.65/SF/mo1 building
- Lease type not stated$2.45–$3.25/SF/mo2 buildings
2 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms1
- 3–4 rooms5
- 5–7 rooms5
- 8–12 rooms1
- 13+ rooms0
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class B5
Hospitals within 5 miles
- Scripps Memorial Hospital La Jolla, La Jolla2.2 mi
- VA San Diego Healthcare System (VA), San Diego3.0 mi
- Scripps Green Hospital, La Jolla3.2 mi
Straight-line miles from the center of the Sorrento Mesa buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 7220 Trade St Sorrento Ridge Corporate Center | B | 1986 | 13,994 SF6 spaces
| 4,095 SF | ~6–10 rooms | $2.45/SF/mo | |
| 9565 Waples St | B | 1990 | 8,637 SF2 spaces
| 6,548 SF | ~10–17 rooms | $2.55–$3.25/SF/mo | |
| 5405 Morehouse Dr | B | 1988 | 6,209 SF2 spaces
| 3,477 SF | ~5–9 rooms | Withheld ask us | |
| 9990 Mesa Rim Rd | B | 1987 | 3,413 SF1 space
| 3,413 SF | ~5–8 rooms | $2.65/SF/mo Gross + Electric & Janitorial | |
| 9200 Scranton Rd | B | 2015 | 1,541 SF1 space
| 1,541 SF | ~2–4 rooms | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Sorrento Mesa | 5 | 33,794 SF | Gross + Electric & Janitorial $2.65 (1) · Lease type not stated $2.45–$3.25 (2) |
| UTC and La Jolla Village | 15 | 255,279 SF | Modified Gross $5.28 (1) |
| Mira Mesa and Miramar | 7 | 326,272 SF | Gross + Utilities $2.25–$3.35 (2) · Gross + Utilities & Janitorial $1.65 (1) |
| Carmel Valley, Del Mar Heights and Rancho Santa Fe | 8 | 52,589 SF | Full Service $4.85–$5.80 (3) · Gross + Electric $4.45 (1) |
| San Diego overall | 246 | 2,136,242 SF | NNN $1.25–$4.25 (41) · Modified Gross $1.50–$5.28 (34) · Gross + Electric $1.75–$4.45 (13) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Sorrento Mesa
How many medical office buildings have space available in Sorrento Mesa?
Sorrento Mesa has 5 buildings with medical office space available as of September 2026: 33,794 SF across 12 listed spaces. Of that, 30,381 SF is marked vacant now, and the largest single space is 6,548 SF, about 10 to 17 exam rooms.
What do medical office leases cost in Sorrento Mesa?
Only one building in Sorrento Mesa publishes an asking rent with a named lease structure: $2.65/SF/month on Gross + Electric & Janitorial, in a Class B building built in 1987. Another two buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Sorrento Mesa?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Sorrento Mesa, the listed spaces break down as 1 for 1 to 2 rooms, 5 for 3 to 4, 5 for 5 to 7 and 1 for 8 to 12.
Which hospitals are near Sorrento Mesa?
Scripps Memorial Hospital La Jolla is the closest hospital, 2.2 miles from the center of the Sorrento Mesa trade area. Also within 5 miles: VA San Diego Healthcare System (VA), San Diego, 3.0 miles; Scripps Green Hospital, La Jolla, 3.2 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Sorrento Mesa availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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