Medical office space · data as of September 2026
591 Camino de la Reina, San Diego Tower 591
1 medical office space listed, 3,830 SF in all, largest 3,830 SF (about 6 to 9 exam rooms). It's vacant now. Asking $3.25/SF/mo, set by the sublessor.
Listed spaces at 591 Camino de la Reina
| Space | Use | Term |
|---|---|---|
| Suite 1250 · 3,830 SF · sublease · available now | Office/Medical | Thru Jun |
Sizes are rentable square feet. Every space listed here is sublease: the sublessor sets the terms, the remaining term comes with it, and the landlord's consent applies. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 3,830 SF
- Largest space
- 3,830 SF
- Fits
- ~6–9 rooms
- Vacant now
- 1 of 1
Asking rent and building facts
Asking rent
- Gross + Electric · sublease$3.25/SF/mobuilding asking range
Mission Valley for comparison
- Gross + Electric$1.75–$2.65/SF/mo3 buildings
- Full Service$2.15–$2.90/SF/mo2 buildings
- Gross + Utilities$2.95/SF/mo2 buildings
- Gross + Electric & Janitorial$1.50–$2.00/SF/mo1 building
- Modified Gross$2.25/SF/mo1 building
Lowest to highest published building asking rents in Mission Valley, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass A
- Built1972, renovated 2018
- Stories12
- Rentable building area176,132 SF
- Parking ratio3.85 per 1,000 SF
- Leased84%
Hospitals near 591 Camino de la Reina
- UC San Diego Health Hillcrest - Hillcrest Medical Center, San Diego0.8 mi
- Scripps Mercy Hospital, San Diego1.0 mi
- Rady Children's Hospital - San Diego (children's), San Diego2.4 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Mission Valley
- 5030 Camino de la Siesta Mission Courtyard 9,326 SF · $2.65/SF/mo
- 5333 Mission Center Rd 32,912 SF · $2.95/SF/mo
- 5353 Mission Center Rd 12,380 SF · $2.95/SF/mo
- 1545 Hotel Cir S Mission Grove Office Park 7,542 SF · $1.81–$1.89/SF/mo
See every building in the Mission Valley trade area guide.
Questions about 591 Camino de la Reina
What medical office space is available at 591 Camino de la Reina?
591 Camino de la Reina in San Diego lists 1 medical office space, 3,830 SF in all, as of September 2026: Suite 1250 · 3,830 SF · sublease · available now. Sizes are rentable square feet.
What is the asking rent at 591 Camino de la Reina?
$3.25/SF/mo, on a Gross + Electric basis, as published for this Class A building, built in 1972 (renovated 2018). Every listed space is sublease, so that figure is the sublessor's ask, not the landlord's.
How many exam rooms fit in the largest space at 591 Camino de la Reina?
About 6 to 9. The largest listed space is 3,830 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1972, renovated 2018.
Which hospitals are near 591 Camino de la Reina?
UC San Diego Health Hillcrest - Hillcrest Medical Center is the closest, 0.8 mile away. Also nearby: Scripps Mercy Hospital, San Diego, 1 mile; Rady Children's Hospital - San Diego (children's), San Diego, 2.4 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 591 Camino de la Reina current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 591 Camino de la Reina
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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