Medical office space · data as of September 2026
2621 S Bristol St, Santa Ana
7 medical office spaces listed, 13,700 SF in all, largest 3,800 SF (about 6 to 9 exam rooms). Six of them are vacant now. Asking $2.00–$2.50/SF/mo on a NNN basis.
Listed spaces at 2621 S Bristol St
| Space | Use | Term |
|---|---|---|
| Suite 105 · 1,400 SF · available now | Office/Medical | 3 - 5 Years |
| Suite 205 · 3,800 SF · available now | Office/Medical | 3 - 5 Years |
| Suite 211 · 1,800 to 2,400 SF · available now | Office/Medical | 3 - 5 Years |
| Suite 203 · 1,000 SF · available now | Medical | 3 Years |
| Suite 303 · 1,200 to 2,400 SF · available now | Office/Medical | 3 - 5 Years |
| Suite 302 · 1,500 SF · available now | Office/Medical | 3 - 5 Years |
| Suite 304 · 1,200 SF · available in 30 days | Office/Medical | 3 - 5 Years |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 13,700 SF
- Largest space
- 3,800 SF
- Fits
- ~6–9 rooms
- Vacant now
- 6 of 7
Asking rent and building facts
Asking rent
- NNN$2.00–$2.50/SF/mobuilding asking range
South Santa Ana for comparison
- Modified Gross$1.69–$2.75/SF/mo3 buildings
- NNN$1.95–$2.50/SF/mo2 buildings
Lowest to highest published building asking rents in South Santa Ana, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass C
- Built1979
- Stories3
- Rentable building area38,308 SF
- Parking ratio6.53 per 1,000 SF
- Leased67%
Hospitals near 2621 S Bristol St
- Coastal Communities Hospital, Santa Ana0.0 mi
- UCI Health - Fountain Valley, Fountain Valley3.0 mi
- Foothill Regional Medical Center, Tustin3.4 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in South Santa Ana
- 1220 Hemlock Way Bristol Southcoast Centre 6,681 SF
- 1120 W Warner Ave 700 SF · $1.69–$2.75/SF/mo
- 2414 S Fairview St 1,200 SF · $2.05/SF/mo
- 1504 Brookhollow Dr 9,585 SF · $1.95–$2.00/SF/mo
See every building in the South Santa Ana trade area guide.
Questions about 2621 S Bristol St
What medical office space is available at 2621 S Bristol St?
2621 S Bristol St in Santa Ana lists 7 medical office spaces, 13,700 SF in all, as of September 2026: Suite 105 · 1,400 SF · available now, Suite 205 · 3,800 SF · available now, Suite 211 · 1,800 to 2,400 SF · available now, Suite 203 · 1,000 SF · available now, Suite 303 · 1,200 to 2,400 SF · available now, Suite 302 · 1,500 SF · available now. Sizes are rentable square feet. Of those, six are vacant now.
What is the asking rent at 2621 S Bristol St?
$2.00–$2.50/SF/mo, on a NNN basis, as published for this Class C building, built in 1979. Taxes, insurance and common-area costs come on top of an NNN rate.
How many exam rooms fit in the largest space at 2621 S Bristol St?
About 6 to 9. The largest listed space is 3,800 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1979.
Which hospitals are near 2621 S Bristol St?
Coastal Communities Hospital is the closest, on the block away. Also nearby: UCI Health - Fountain Valley, Fountain Valley, 3.0 miles; Foothill Regional Medical Center, Tustin, 3.4 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 2621 S Bristol St current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 2621 S Bristol St
Send your size and timing. Live availability and terms for this building come back within one business day.
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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