Medical office space · data as of September 2026
3300 Irvine Ave, Newport Beach Newport Irvine Medical Center
6 medical office spaces listed, 50,442 SF in all, largest 12,517 SF (about 20 to 32 exam rooms). Six of them are vacant now. The landlord quotes rent on request.
Listed spaces at 3300 Irvine Ave
| Space | Use | Term |
|---|---|---|
| Suite 112 · 9,682 SF · available now | Medical | Negotiable |
| Suite 106 · 8,247 SF · available now | Medical | Negotiable |
| Suite 110 · 5,258 SF · available now | Medical | Negotiable |
| Suite 116 · 2,430 SF · available now | Medical | Negotiable |
| Suite 315 · 12,517 SF · available now | Medical | Negotiable |
| Suite 308 · 2,500 to 12,308 SF · available now | Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 50,442 SF
- Largest space
- 12,517 SF
- Fits
- ~20–32 rooms
- Vacant now
- 6 of 6
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Newport Beach, 22 of 37 buildings do the same.
Newport Beach for comparison
- Full Service$2.99–$6.00/SF/mo5 buildings
- Modified Gross$2.50–$4.95/SF/mo3 buildings
- NNN$3.98–$5.25/SF/mo3 buildings
- Lease type not stated$3.10/SF/mo1 building
Lowest to highest published building asking rents in Newport Beach, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1980, renovated 1997
- Stories3
- Rentable building area75,000 SF
- Parking ratio3.73 per 1,000 SF
- Leased33%
Hospitals near 3300 Irvine Ave
- College Hospital Costa Mesa, Costa Mesa2.1 mi
- Coastal Communities Hospital, Santa Ana3.6 mi
- Hoag Memorial Hospital Presbyterian, Newport Beach3.8 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Newport Beach
- 20311 Birch St 2,012 SF · $4.00/SF/mo
- 20072 SW Birch St Optimum Medical 1,797 SF
- 3701 Birch St 6,535 SF · $4.50/SF/mo
- 2372-2382 SE Bristol St Bristol Spruce Bldg 5,965 SF · $3.98/SF/mo
See every building in the Newport Beach trade area guide.
Questions about 3300 Irvine Ave
What medical office space is available at 3300 Irvine Ave?
3300 Irvine Ave in Newport Beach lists 6 medical office spaces, 50,442 SF in all, as of September 2026: Suite 112 · 9,682 SF · available now, Suite 106 · 8,247 SF · available now, Suite 110 · 5,258 SF · available now, Suite 116 · 2,430 SF · available now, Suite 315 · 12,517 SF · available now, Suite 308 · 2,500 to 12,308 SF · available now. Sizes are rentable square feet. Of those, six are vacant now.
What is the asking rent at 3300 Irvine Ave?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 3300 Irvine Ave?
About 20 to 32. The largest listed space is 12,517 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1980, renovated 1997.
Which hospitals are near 3300 Irvine Ave?
College Hospital Costa Mesa is the closest, 2.1 miles away. Also nearby: Coastal Communities Hospital, Santa Ana, 3.6 miles; Hoag Memorial Hospital Presbyterian, Newport Beach, 3.8 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 3300 Irvine Ave current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 3300 Irvine Ave
Send your size and timing. Live availability and terms for this building come back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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