Medical office space · data as of September 2026
16485 Laguna Canyon Rd, Irvine Laguna Canyon Plaza
5 medical office spaces listed, 20,500 SF in all, largest 6,500 SF (about 10 to 16 exam rooms). Five of them are vacant now. The landlord quotes rent on request.
Listed spaces at 16485 Laguna Canyon Rd
| Space | Use | Term |
|---|---|---|
| Suite 120 · 1,000 to 5,000 SF · available now | Medical | Negotiable |
| Suite 100 · 500 to 2,500 SF · available now | Medical | Negotiable |
| Suite 250 · 2,500 to 6,500 SF · available now | Medical | Negotiable |
| Suite 230 · 2,000 to 3,500 SF · available now | Medical | Negotiable |
| Suite 300 · 3,000 SF · available now | Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 20,500 SF
- Largest space
- 6,500 SF
- Fits
- ~10–16 rooms
- Vacant now
- 5 of 5
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Irvine Spectrum, 5 of 12 buildings do the same.
Irvine Spectrum for comparison
- NNN$3.25–$4.75/SF/mo5 buildings
- Full Service$3.00/SF/mo1 building
Lowest to highest published building asking rents in Irvine Spectrum, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1991, renovated 1999
- Stories3
- Rentable building area64,313 SF
- Parking ratio3.80 per 1,000 SF
- Leased42%
Hospitals near 16485 Laguna Canyon Rd
- Hoag Orthopedic Institute, Irvine0.6 mi
- Memorialcare Saddleback Medical Center, Laguna Hills4.8 mi
- Foothill Regional Medical Center, Tustin6.3 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Irvine Spectrum
- 6865 Alton Pky 1,295 SF · $3.25/SF/mo
- 16300 Sand Canyon Ave Sand Canyon Medical #1 11,242 SF
- 16100 Sand Canyon Ave Sand Canyon Medical Center 2,736 SF
- 15825 Laguna Canyon Rd Spectrum Medical Plaza 8,200 SF · $3.95/SF/mo
See every building in the Irvine Spectrum trade area guide.
Questions about 16485 Laguna Canyon Rd
What medical office space is available at 16485 Laguna Canyon Rd?
16485 Laguna Canyon Rd in Irvine lists 5 medical office spaces, 20,500 SF in all, as of September 2026: Suite 120 · 1,000 to 5,000 SF · available now, Suite 100 · 500 to 2,500 SF · available now, Suite 250 · 2,500 to 6,500 SF · available now, Suite 230 · 2,000 to 3,500 SF · available now, Suite 300 · 3,000 SF · available now. Sizes are rentable square feet. Of those, five are vacant now.
What is the asking rent at 16485 Laguna Canyon Rd?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 16485 Laguna Canyon Rd?
About 10 to 16. The largest listed space is 6,500 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1991, renovated 1999.
Which hospitals are near 16485 Laguna Canyon Rd?
Hoag Orthopedic Institute is the closest, 0.6 mile away. Also nearby: Memorialcare Saddleback Medical Center, Laguna Hills, 4.8 miles; Foothill Regional Medical Center, Tustin, 6.3 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 16485 Laguna Canyon Rd current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 16485 Laguna Canyon Rd
Send your size and timing. Live availability and terms for this building come back within one business day.
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We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.
Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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