Medical office space · data as of September 2026
Medical office space for lease in Costa Mesa
13 buildings with 57,603 SF of medical space available across 18 listed spaces. Eight buildings publish an asking rent; no class has five or more on one lease structure, too few to call a figure typical.
Costa Mesa's published rents this September come on three different lease structures, and they aren't the same kind of number: NNN in four buildings, Full Service in two and Modified Gross in two.
NNN runs $2.25 to $3.05/SF/month here, Full Service $2.50 to $2.73 and Modified Gross $2.65 to $2.70. Those ranges sit side by side on the page, but they don't measure the same thing. NNN puts taxes, insurance and common-area costs on top of the rate; Full Service rolls operating costs and utilities into the rate; Modified Gross splits operating costs between landlord and tenant, lease by lease. The only fair comparison is total occupancy cost: the rent plus everything the lease puts on top of it.
The second thing to know is about location. College Hospital Costa Mesa is 0.8 mile from the center of the trade area. The lease read: distance to a campus is the one thing about a suite you can't build, negotiate or fix later. Pay for the location you need, and make the buildings compete on everything else.
Short version: landlords in Costa Mesa quote three lease structures, and College Hospital Costa Mesa sits 0.8 mile out. Pay for the distance that matters and negotiate the rest. How often does your practice make the trip to College Hospital Costa Mesa now?
Costa Mesa at a glance
- Buildings
- 13
- Medical space available
- 57,603 SF
- Vacant now
- 33,775 SF
- Largest single space
- 8,567 SF
Asking rents by lease structure
- NNN$2.25–$3.17/SF/mo4 buildings
- Full Service$2.50–$2.95/SF/mo2 buildings
- Modified Gross$2.65–$2.70/SF/mo2 buildings
5 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms3
- 3–4 rooms7
- 5–7 rooms4
- 8–12 rooms1
- 13+ rooms3
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class A2
- Class B8
- Class C3
Hospitals within 5 miles
- College Hospital Costa Mesa, Costa Mesa0.8 mi
- Hoag Memorial Hospital Presbyterian, Newport Beach3.0 mi
- Coastal Communities Hospital, Santa Ana3.6 mi
- UCI Health - Fountain Valley, Fountain Valley3.6 mi
- Memorialcare Orange Coast Medical Center, Fountain Valley3.6 mi
Straight-line miles from the center of the Costa Mesa buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 890 W Baker St | C | 1980 | 16,192 SF2 spaces
| 8,567 SF | ~14–22 rooms | $2.70/SF/mo Modified Gross | |
| 3150 Bristol St Canvas North | A | 1987 | 8,458 SF1 space
| 8,458 SF | ~14–21 rooms | $2.50–$2.95/SF/mo Full Service | |
| 1202 Bristol St Bristol Newport Medical Plaza | B | 2007 | 7,015 SF1 space
| 7,015 SF | ~11–18 rooms | Withheld ask us | |
| 1520 Nutmeg Pl Harbor Nutmeg Plaza | B | 1982 | 5,735 SF2 spaces
| 2,917 SF | ~4–7 rooms | $2.65/SF/mo Modified Gross | |
| 1901 Newport Blvd Newport Boulevard | B | 1985 | 4,552 SF2 spaces
| 2,461 SF | ~4–6 rooms | Withheld ask us | |
| 204 E 17th St | B | 1978 | 4,437 SF2 spaces
| 2,257 SF | ~3–5 rooms | $2.85/SF/mo NNN | |
| 2314 Newport Blvd | B | 2008 | 3,350 SF1 space
| 3,350 SF | ~5–8 rooms | $2.25/SF/mo NNN | |
| 1640 Newport Blvd Pacific Medical Plaza | A | 2007 | 2,735 SF2 spaces
| 1,390 SF | ~2–3 rooms | Withheld ask us | |
| 1530 Baker St Mesa Verde Medical Center | B | 1961 | 1,630 SF1 space
| 1,630 SF | ~2–4 rooms | $2.92–$3.17/SF/mo NNN | |
| 1503 S Coast Dr South Coast Executive Centre | B | 1979 | 1,200 SF1 space
| 1,200 SF | ~2–3 rooms | $2.50/SF/mo Full Service | |
| 2077 Harbor Blvd | C | 1964 | 1,000 SF1 space
| 1,000 SF | ~1–2 rooms | Withheld ask us | |
| 181 E 18th St | C | 1959 | 900 SF1 space
| 900 SF | ~1–2 rooms | $3.00/SF/mo NNN | |
| 3313 Hyland Ave SOCO & The OC Mix | B | 2009 | 399 SF1 space
| 399 SF | ~1 room | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Costa Mesa | 13 | 57,603 SF | NNN $2.25–$3.17 (4) · Full Service $2.50–$2.95 (2) · Modified Gross $2.65–$2.70 (2) |
| Newport Beach | 37 | 383,867 SF | Full Service $2.99–$6.00 (5) · Modified Gross $2.50–$4.95 (3) · NNN $3.98–$5.25 (3) |
| Fountain Valley | 7 | 48,905 SF | Full Service $3.60 (1) · Modified Gross $1.60 (1) |
| South Santa Ana | 6 | 40,228 SF | Modified Gross $1.69–$2.75 (3) · NNN $1.95–$2.50 (2) |
| Orange County overall | 317 | 2,274,339 SF | NNN $1.15–$5.50 (67) · Modified Gross $1.25–$4.95 (49) · Full Service $1.25–$6.00 (47) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Questions about medical office space in Costa Mesa
How many medical office buildings have space available in Costa Mesa?
Costa Mesa has 13 buildings with medical office space available as of September 2026: 57,603 SF across 18 listed spaces. Of that, 33,775 SF is marked vacant now, and the largest single space is 8,567 SF, about 14 to 22 exam rooms.
What do medical office leases cost in Costa Mesa?
In Costa Mesa, eight buildings publish an asking rent with a named lease structure, but no class has five or more on one structure, too few to call any figure typical: Class B on NNN in three, Class A on Full Service in one and Class B on Full Service in one. Another five buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Costa Mesa?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Costa Mesa, the listed spaces break down as 3 for 1 to 2 rooms, 7 for 3 to 4, 4 for 5 to 7, 1 for 8 to 12 and 3 for 13 or more.
Which hospitals are near Costa Mesa?
College Hospital Costa Mesa is the closest hospital, 0.8 mile from the center of the Costa Mesa trade area. Also within 5 miles: Hoag Memorial Hospital Presbyterian, Newport Beach, 3.0 miles; Coastal Communities Hospital, Santa Ana, 3.6 miles; UCI Health - Fountain Valley, Fountain Valley, 3.6 miles; Memorialcare Orange Coast Medical Center, Fountain Valley, 3.6 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Costa Mesa availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Costa Mesa
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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