Medical office space · data as of September 2026
24355 Lyons Ave, Santa Clarita Lyons Medical Office Building
2 medical office spaces listed, 6,345 SF in all, largest 5,021 SF (about 8 to 13 exam rooms). One of them is vacant now. The landlord quotes rent on request.
Listed spaces at 24355 Lyons Ave
| Space | Use | Term |
|---|---|---|
| Suite 210 · 2,000 to 5,021 SF · available now | Office/Medical | Negotiable |
| Suite 214 · 1,324 SF · available in 60 days | Office/Medical | Negotiable |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 6,345 SF
- Largest space
- 5,021 SF
- Fits
- ~8–13 rooms
- Vacant now
- 1 of 2
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Santa Clarita Valley, 13 of 29 buildings do the same.
Santa Clarita Valley for comparison
- NNN$1.50–$2.77/SF/mo7 buildings
- Full Service$2.95–$3.05/SF/mo3 buildings
- Modified Gross$2.15–$4.16/SF/mo3 buildings
- Gross + Electric$1.95–$2.25/SF/mo1 building
Lowest to highest published building asking rents in Santa Clarita Valley, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1989
- Stories2
- Rentable building area50,899 SF
- Parking ratio4.00 per 1,000 SF
- Leased90%
Hospitals near 24355 Lyons Ave
- Henry Mayo Newhall Hospital, Valencia1.3 mi
- LAC/Olive View-UCLA Medical Center, Sylmar7.5 mi
- Providence Holy Cross Medical Center, Mission Hills9.0 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Santa Clarita Valley
- 25050 Peachland Ave Plaza Posada Professional Office 5,516 SF · $2.50/SF/mo
- 23929 McBean Pky Building F 3,644 SF
- 23861 McBean Pky Building E 4,931 SF
- 23206 Lyons Ave 2,211 SF
See every building in the Santa Clarita Valley trade area guide.
Questions about 24355 Lyons Ave
What medical office space is available at 24355 Lyons Ave?
24355 Lyons Ave in Santa Clarita lists 2 medical office spaces, 6,345 SF in all, as of September 2026: Suite 210 · 2,000 to 5,021 SF · available now, Suite 214 · 1,324 SF · available in 60 days. Sizes are rentable square feet. Of those, one is vacant now.
What is the asking rent at 24355 Lyons Ave?
Not published. The landlord quotes on request, once the size and use are known.
How many exam rooms fit in the largest space at 24355 Lyons Ave?
About 8 to 13. The largest listed space is 5,021 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1989.
Which hospitals are near 24355 Lyons Ave?
Henry Mayo Newhall Hospital is the closest, 1.3 miles away. Also nearby: LAC/Olive View-UCLA Medical Center, Sylmar, 7.5 miles; Providence Holy Cross Medical Center, Mission Hills, 9.0 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 24355 Lyons Ave current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 24355 Lyons Ave
Send your size and timing. Live availability and terms for this building come back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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