Medical office space · data as of September 2026
Medical office space for lease in Santa Monica
38 buildings with 293,579 SF of medical space available across 118 listed spaces. The largest like group, eight Class B buildings on Modified Gross, asks a median $3.95/SF/month.
Santa Monica's medical market is anchored by two hospitals a few blocks apart: UCLA Health Santa Monica Medical Center on 16th Street and Providence Saint John's Health Center on Santa Monica Boulevard. The office buildings around those two campuses, and along Wilshire and Santa Monica Boulevards between them, hold most of the city's physician space. Practices that need privileges at either hospital, or referrals from their medical groups, usually want to be within walking distance.
Closer to the ocean, downtown and Ocean Park Boulevard offer smaller buildings suited to wellness, dermatology, physical therapy and concierge practices that value a Westside location over hospital proximity. Newer medical space is scarce, so well-located second-generation suites lease quickly.
Rents run high and Full Service and Modified Gross quotes are the norm, so read what is included before comparing buildings. Parking is tight near both hospitals; confirm patient parking and validation terms in writing, and check the city's rules early if your plans need new plumbing or signage.
Santa Monica at a glance
- Buildings
- 38
- Medical space available
- 293,579 SF
- Vacant now
- 232,435 SF
- Largest single space
- 20,210 SF
Asking rents by lease structure
- Full Service$2.95–$6.50/SF/mo8 buildings
- Modified Gross$3.45–$5.50/SF/mo8 buildings
- NNN$3.55–$4.50/SF/mo3 buildings
- Lease type not stated$2.33–$4.50/SF/mo3 buildings
16 buildings withhold pricing or don't publish it. Those numbers come from the landlords on request.
Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs on top of base rent; Modified Gross splits them. Compare structures, not just rates. These ranges span every building class and age; the questions below compare like with like.
Available spaces by size
- 1–2 rooms25
- 3–4 rooms49
- 5–7 rooms26
- 8–12 rooms7
- 13+ rooms5
Room counts assume 350 to 500 usable SF per exam room, with rentable area 10% to 20% above usable.
Building class
- Class A6
- Class B22
- Class C10
Hospitals within 5 miles
- Santa Monica - UCLA Medical Center & Orthopaedic Hospital, Santa Monica0.3 mi
- Saint John's Health Center, Santa Monica0.3 mi
- VA Greater Los Angeles Healthcare System (VA), Los Angeles2.4 mi
- Ronald Reagan UCLA Medical Center, Los Angeles3.4 mi
- Cedars-Sinai Marina del Rey Hospital, Marina Del Rey3.8 mi
Straight-line miles from the center of the Santa Monica buildings to the Census Bureau geocode of each hospital's address on the CMS hospital list.
Buildings with medical space available
| Building | Class | Built | Medical space | Largest space | Fits | Asking rent | |
|---|---|---|---|---|---|---|---|
| 2701 Ocean Park Blvd Ocean Park Plaza | B | 1987 | 71,602 SF9 spaces
| 20,210 SF | ~33–52 rooms | Withheld ask us | |
| 2001 Santa Monica Blvd | B | 1976 | 28,757 SF16 spaces
| 3,488 SF | ~5–9 rooms | $4.90/SF/mo Full Service | |
| 2716 Ocean Park Blvd | A | 1978 | 22,898 SF7 spaces
| 5,923 SF | ~9–15 rooms | $3.50–$3.95/SF/mo | |
| 2021 Santa Monica Blvd | A | 1965 | 20,377 SF9 spaces
| 6,273 SF | ~10–16 rooms | Withheld ask us | |
| 1807 Wilshire Blvd Bldg B | B | 1981 | 13,475 SF3 spaces
| 5,570 SF | ~9–14 rooms | Withheld ask us | |
| 2825 Santa Monica Blvd | B | 1984 | 10,671 SF2 spaces
| 9,301 SF | ~15–24 rooms | $5.50/SF/mo Modified Gross | |
| 2500-2512 Santa Monica Blvd | C | 1939 | 8,894 SF4 spaces
| 3,459 SF | ~5–8 rooms | $3.55/SF/mo NNN | |
| 1411-1413 5th St Pacific Court | B | 1989 | 8,600 SF2 spaces
| 5,900 SF | ~9–15 rooms | $3.75/SF/mo Modified Gross | |
| 3435 Ocean Park Blvd | B | 1986 | 7,911 SF6 spaces
| 2,407 SF | ~4–6 rooms | $3.45–$3.95/SF/mo Modified Gross | |
| 1451-1457 3rd Street Promenade Promenade Gateway | A | 1989 | 7,559 SF3 spaces
| 3,099 SF | ~5–8 rooms | Withheld ask us | |
| 2811 Wilshire Blvd Wilshire Tower | A | 1973 | 7,317 SF4 spaces
| 2,235 SF | ~3–5 rooms | $5.95/SF/mo Full Service | |
| 3331 Ocean Park Blvd | B | 1973 | 6,600 SF2 spaces
| 3,300 SF | ~5–8 rooms | $3.95/SF/mo Modified Gross | |
| 2001 Wilshire Blvd 2001 Wilshire | C | 1980 | 6,170 SF2 spaces
| 3,122 SF | ~5–8 rooms | $2.95/SF/mo Full Service | |
| 2428 Santa Monica Blvd Parkside Medical Center | B | 1923 | 6,169 SF5 spaces
| 2,413 SF | ~4–6 rooms | $6.31/SF/mo Full Service | |
| 1304 15th St Santa Monica Physician's Center | B | 1972 | 5,653 SF5 spaces
| 3,300 SF | ~5–8 rooms | Withheld ask us | |
| 1328 16th St | C | 1986 | 5,319 SF1 space
| 5,319 SF | ~8–13 rooms | Withheld ask us | |
| 2901 Wilshire Blvd Yale-Wilshire Medical Bldg | A | 1965 | 4,728 SF2 spaces
| 2,982 SF | ~4–7 rooms | Withheld ask us | |
| 1245 16th St | B | 1988 | 4,631 SF2 spaces
| 3,741 SF | ~6–9 rooms | Withheld ask us | |
| 1243 7th St | C | 1977 | 4,368 SF2 spaces
| 3,015 SF | ~5–7 rooms | Withheld ask us | |
| 2914-2936 Wilshire Blvd Wilshire Sanford Bldg | C | 1949 | 4,000 SF2 spaces
| 2,000 SF | ~3–5 rooms | Withheld ask us | |
| 1250 6th St Arizona Place | B | 1986 | 3,519 SF2 spaces
| 2,241 SF | ~3–5 rooms | $4.75/SF/mo Full Service | |
| 1450 10th St | B | 1984 | 3,506 SF2 spaces
| 2,075 SF | ~3–5 rooms | Withheld ask us | |
| 900 Wilshire Blvd | B | 1997 | 3,409 SF1 space
| 3,409 SF | ~5–8 rooms | Withheld ask us | |
| 1227 Lincoln Blvd Lincoln Medical Building | B | 1959 | 3,360 SF3 spaces
| 1,680 SF | ~2–4 rooms | $5.30/SF/mo Modified Gross | |
| 1260 15th St Santa Monica Medical Plz | A | 1973 | 3,154 SF3 spaces
| 1,194 SF | ~1–3 rooms | $6.50/SF/mo Full Service | |
| 2221 Lincoln Blvd | C | 1973 | 2,967 SF2 spaces
| 2,007 SF | ~3–5 rooms | $3.50–$4.50/SF/mo | |
| 3201 Wilshire Blvd | B | 1992 | 2,632 SF4 spaces
| 1,565 SF | ~2–4 rooms | Withheld ask us | |
| 1908 Santa Monica Blvd White Medical Center | C | 1946 | 2,201 SF1 space
| 2,201 SF | ~3–5 rooms | $3.75/SF/mo NNN | |
| 319-335 Wilshire Blvd | B | 1925 | 2,184 SF1 space
| 2,184 SF | ~3–5 rooms | $3.95/SF/mo Modified Gross | |
| 2915 Santa Monica Blvd | B | 1998 | 2,000 SF2 spaces
| 1,000 SF | ~1–2 rooms | $3.95/SF/mo Modified Gross | |
| 3200 Santa Monica Blvd | C | 1960 | 1,600 SF2 spaces
| 1,000 SF | ~1–2 rooms | $2.33–$3.00/SF/mo | |
| 1531 6th St Anacapa | B | 2003 | 1,540 SF1 space
| 1,540 SF | ~2–4 rooms | Withheld ask us | |
| 1460 7th St The Torcello | B | 1992 | 1,362 SF1 space
| 1,362 SF | ~2–3 rooms | $4.50/SF/mo Modified Gross | |
| 2730 Wilshire Blvd | B | 1985 | 1,315 SF1 space
| 1,315 SF | ~2–3 rooms | $5.75/SF/mo Full Service | |
| 2222 Santa Monica Blvd | C | 1961 | 1,209 SF1 space
| 1,209 SF | ~2–3 rooms | $4.50/SF/mo Full Service | |
| 1418 7th St Genoa Apartments | B | 2009 | 872 SF1 space
| 872 SF | ~1–2 rooms | $4.50/SF/mo NNN | |
| 1137 2nd St | C | 1942 | 650 SF1 space
| 650 SF | ~1 room | Withheld ask us | |
| 1247 7th St | B | 1986 | 400 SF1 space
| 400 SF | ~1 room | Withheld ask us |
Availability and asking rates change frequently and are subject to verification. Current terms are confirmed before any tour.
Compared to nearby
| Area | Buildings | Medical space | Published asking rents ($/SF/mo, buildings) |
|---|---|---|---|
| Santa Monica | 38 | 293,579 SF | Full Service $2.95–$6.50 (8) · Modified Gross $3.45–$5.50 (8) · NNN $3.55–$4.50 (3) |
| Beverly Hills | 55 | 466,177 SF | Full Service $2.95–$10.00 (13) · Modified Gross $3.00–$8.50 (13) · NNN $5.00–$7.74 (3) |
| West Los Angeles and Century City | 20 | 200,079 SF | Full Service $1.50–$5.45 (9) · Modified Gross $3.95–$5.25 (3) · NNN $4.70–$5.50 (2) |
| Marina del Rey and Venice | 12 | 91,947 SF | Modified Gross $1.99–$5.00 (5) · Full Service $2.80–$4.97 (2) · NNN $2.25–$3.50 (2) |
| Los Angeles overall | 849 | 6,324,965 SF | Modified Gross $1.22–$8.50 (206) · Full Service $1.15–$10.00 (176) · NNN $1.10–$7.74 (143) |
Lowest to highest published building asking rents, grouped by lease structure; the three most common structures are shown. Each range mixes building classes and ages. See the full rent trends report.
Trade area context
Saint John's Health Center sits 0.28 mile from the center of the Santa Monica trade area, and UCLA Health Santa Monica is 0.36 mile. Referral proximity is close to a given here. Getting patients to your door is the harder part.
- 82,244 residents in the ZIP areas, 18.9% of them 65 or older, 96.3% insured.
- Median household income runs from $95,139 (90404) to $121,925 (90403), and the margins overlap.
- 12.1% of households have no vehicle (22.6% in 90401), and 75.8% of occupied homes are renter-occupied.
- Wilshire Boulevard counts 24,105 to 32,157 vehicles a day near listed buildings, and Santa Monica Boulevard 13,015 to 30,237 (CoStar, 2026 counts).
The real estate read: with hospitals this close, what separates one building from the next is parking and access. Get the ratio, the validation terms and the monthly charge into the lease, not just the tour. Landlords describe a garage as an amenity right up until you ask what it costs.
Short version: two hospitals within 0.36 mile, a renter-heavy base, and a meaningful share of households without a car. How do most of your patients reach your door today?
Sources: Census Bureau ACS 2020-2024 5-year; CMS Hospital General Information; CoStar traffic count reports (October 2026). ZIP areas extend beyond the city limits.
Questions about the Santa Monica trade area
Which hospitals are closest to the Santa Monica trade area?
Saint John's Health Center is 0.28 mile from the trade area center and UCLA Health Santa Monica is 0.36 mile; both have emergency departments. VA Greater Los Angeles Healthcare System is 2.80 miles from the center (CMS Hospital General Information).
Is Santa Monica a federally designated shortage area?
HRSA files show no active primary care, dental or mental health designation covering a census tract in these ZIP areas. A primary care and a mental health designation that touched them were both withdrawn on January 2, 2024.
How many Santa Monica households have no vehicle?
12.1% across the four ZIP areas, and 22.6% in 90401 (ACS 2020-2024 5-year). That is worth a line in any parking discussion.
Questions about medical office space in Santa Monica
How many medical office buildings have space available in Santa Monica?
Santa Monica has 38 buildings with medical office space available as of September 2026: 293,579 SF across 118 listed spaces. Of that, 232,435 SF is marked vacant now, and the largest single space is 20,210 SF, about 33 to 52 exam rooms.
What do medical office leases cost in Santa Monica?
In Santa Monica, Class B buildings on Modified Gross ask $3.70 to $5.50/SF/month, with a median of $3.95, across eight buildings built from 1925 to 1998. Each building counts once, at the middle of its published range. Across the Westside, Class B buildings on Modified Gross ask a median $4.50/SF/month. The remaining 14 priced buildings sit in classes and structures with fewer than five buildings each, too few to call typical. Another 16 buildings post no asking rent; those landlords quote on request. Full Service includes operating costs and utilities, NNN adds taxes, insurance and common-area costs on top, and Modified Gross splits them, so compare total occupancy cost, not the headline rate.
How much space does a medical practice need in Santa Monica?
About 385 to 600 rentable square feet per exam room. That's 350 to 500 usable square feet (the room plus its share of waiting, work areas, storage, restrooms and halls), and leases are quoted in rentable square feet, which run 10% to 20% above usable in multi-tenant medical buildings. In Santa Monica, the listed spaces break down as 25 for 1 to 2 rooms, 49 for 3 to 4, 26 for 5 to 7, 7 for 8 to 12 and 5 for 13 or more.
Which hospitals are near Santa Monica?
Santa Monica - UCLA Medical Center & Orthopaedic Hospital is the closest hospital, 0.3 mile from the center of the Santa Monica trade area. Also within 5 miles: Saint John's Health Center, Santa Monica, 0.3 mile; VA Greater Los Angeles Healthcare System (VA), Los Angeles, 2.4 miles; Ronald Reagan UCLA Medical Center, Los Angeles, 3.4 miles; Cedars-Sinai Marina del Rey Hospital, Marina Del Rey, 3.8 miles. Distances are straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
How current is the Santa Monica availability?
It's from the September 2026 survey of medical office availability. Spaces lease and asking terms change between monthly pulls, so current availability, rent and tenant improvement allowance are confirmed with each landlord before any tour.
Send me what fits in Santa Monica
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Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
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