Medical office space · data as of September 2026
39959 Sierra Hwy, Palmdale Bldg A
1 medical office space listed, 2,270 SF in all, largest 2,270 SF (about 3 to 5 exam rooms). It's vacant now. The landlord quotes rent on request. Across Antelope Valley, seven Class B NNN buildings built in 1990 or later ask a median $2.36/SF/month.
Listed spaces at 39959 Sierra Hwy
| Space | Use | Term |
|---|---|---|
| Suite A220 · 2,270 SF · available now | Office/Medical | 3 - 5 Years |
Sizes are rentable square feet. Listed with the building as of September 2026. Availability, asking terms and tenant improvement allowance are confirmed with the landlord before any tour.
- Medical space listed
- 2,270 SF
- Largest space
- 2,270 SF
- Fits
- ~3–5 rooms
- Vacant now
- 1 of 1
Asking rent and building facts
Asking rent
The landlord withholds pricing for this building and quotes on request. In Antelope Valley, 5 of 23 buildings do the same.
Antelope Valley for comparison
- NNN$1.10–$2.75/SF/mo11 buildings
- Modified Gross$1.30–$2.30/SF/mo6 buildings
- Lease type not stated$2.30/SF/mo1 building
Lowest to highest published building asking rents in Antelope Valley, grouped by lease structure. Full Service includes operating costs and utilities; NNN adds taxes, insurance and common-area costs; Modified Gross splits them.
Building
- Building classClass B
- Built1991, renovated 2017
- Stories2
- Rentable building area66,136 SF
- Parking ratio4.16 per 1,000 SF
- Leased97%
Hospitals near 39959 Sierra Hwy
- Palmdale Regional Medical Center, Palmdale2.0 mi
- Antelope Valley Hospital, Lancaster5.9 mi
Straight-line miles from the Census Bureau geocode of each hospital's address on the CMS hospital list.
Other buildings with medical space in Antelope Valley
- 40015 Sierra Hwy Bldg B 3,267 SF
- 843 Auto Center Dr Building 2 2,940 SF · $2.36/SF/mo
- 847 Auto Center Dr Building 5 1,203 SF · $2.36/SF/mo
- 520-540 W Palmdale Blvd West Palmdale Plaza 1,729 SF · $1.89/SF/mo
See every building in the Antelope Valley trade area guide.
Questions about 39959 Sierra Hwy
What medical office space is available at 39959 Sierra Hwy?
39959 Sierra Hwy in Palmdale lists 1 medical office space, 2,270 SF in all, as of September 2026: Suite A220 · 2,270 SF · available now. Sizes are rentable square feet.
What is the asking rent at 39959 Sierra Hwy?
Not published. The landlord quotes on request, once the size and use are known. Across Antelope Valley, seven Class B NNN buildings built in 1990 or later ask a median $2.36/SF/month. Each building counts once, at the middle of its published range.
How many exam rooms fit in the largest space at 39959 Sierra Hwy?
About 3 to 5. The largest listed space is 2,270 SF, and planning runs 385 to 600 rentable SF per exam room (350 to 500 usable, plus a 10% to 20% load factor, the share of common areas billed to each tenant). Plumbing, ADA restrooms and HVAC decide whether that count works in a building that wasn't built for exam rooms. This one dates to 1991, renovated 2017.
Which hospitals are near 39959 Sierra Hwy?
Palmdale Regional Medical Center is the closest, 2.0 miles away. Also nearby: Antelope Valley Hospital, Lancaster, 5.9 miles. Distances are straight-line miles to each hospital's address on the CMS hospital list.
Is the availability at 39959 Sierra Hwy current?
It's from the September 2026 survey of medical office availability. Availability, rent and tenant improvement allowance are confirmed with the landlord before any tour.
Ask about 39959 Sierra Hwy
Send your size and timing. Live availability and terms for this building come back within one business day.
Sent.
We typically reply within one business day. Prefer to talk now? Call (619) 796-3390.

Your advisor
Jamal Brown
Real Estate Broker · CA DRE #01780052
Jamal has spent more than 23 years in commercial real estate and has negotiated and audited more than 1,000 leases. He represents medical practices as tenants and buyers, never landlords, across Los Angeles, Orange County, San Diego and the Inland Empire. Every request sent through this site gets a reply within one business day.
Recent medical office deals
8 practices · 20,061 SF leased · $2.7M building purchase
- 23500 Hawthorne Blvd$2.7MTorrance · owner-user purchase, $500K below asking
- X-Ray Medical Group5,200 SFLa Mesa
- Lighthouse Pediatrics4,261 SFTorrance
- Caring Physicians3,600 SFLa Mesa
- Desert Trauma Surgeons2,000 SFLynwood
- Dr. Hannon1,600 SFBeverly Hills
- Achilles Podiatry1,200 SFLa Mesa
- Dr. Kenith Paresa1,200 SFSanta Monica
- Little Bellies1,000 SFIrvine